Based on hundreds of communications I have received from readers of this blog, I reject the often-asserted “fact” that most people these days have the attention span of a gnat. Therefore, I am publishing the full text, rather than a few excerpts of this remarkable document from 1876 in which a prominent physician offers his first-hand observations on the medical benefits of Coca leaf.
While many of Dr. Christison’s observations are directed toward the role of Coca leaf in relieving fatigue brought on by exercise and poor physical conditioning, scattered throughout these pages are tidbits of information that suggest what many other Doctors later confirmed – that Coca leaf is both a preventative and a remedy for a wide range of conditions and diseases, and that it offers these benefits with absolutely no undesirable side-effects.
Readers of this blog may have read other posts in which I present evidence that Coca leaf could be of great benefit for people who suffer from congestive heart failure, migraines, ME/CFS, inflammatory bowel disease, Alzheimer’s, fibromyalgia, obesity, reaction to chemotherapy, arthritis, and many other terrible diseases that have a basis in whole body inflammation. Most relevant, in my opinion, is that in his observations Dr. Christison affirms that the use of Coca leaf in non-addictive and has none of the effects of ingesting Cocaine. Put in contemporary language, Dr. Christison is clear that nobody could possibly drink enough Coca leaf tea to get high.
So if you are not a gnat, and if you want to understand the medical applications of Coca leaf from the unbiased perspective of a celebrated physician in an article published in one of the leading medical journals of his time, please read on.
Observations On The Effects Of Cuca, Or Coca, The Leaves Of Erythroxylon Coca
By Sir Robert Christison, Bart., M.D., D.C L., Ll.D., F.R.S.Ed.,
President of the British Medical Association; Ordinary Physician to the Queen in Scotland; Professor of Materia Medica in the University of Edinburgh
(in) British Medical Journal, April 29, 1876
THE brief notice taken in my introductory address to this Society in November last, of the restorative and preservative virtues of the Peruvian Cuca or coca-leaf against bodily fatigue from severe exercise, has led to numberless references to me by friends and strangers in all parts of the kingdom for information as to its effects, its safety, its applicability to the treatment of some states of disease, and the quarters in which it may be obtained.
As I am not aware of any trials of it having been made in this country, either earlier than mine or so extensive, and as I shall probably best answer the many inquiries sent me by publishing an account of these experiments, I have been induced to present the following narrative to the Botanical Society. The inquiry, of which my recent trials form a part, is very far from being complete, because my supply was quite inadequate till the other day, when I received a sufficiency through the kind services of my colleague Professor Wyville Thomson, of the Challenger expedition.
But the facts already obtained will probably interest not a few at the present time, were it for no more than that they set at rest all doubts that the more important of the effects of Cuca, experienced in its own country by the natives of Peru and the neighbouring states, may be equally produced in Europeans at home; and that, contrary to what seems universally believed in Peru, the virtues of the leaf may be preserved, with due care, for many years.
Since my observations must bear reference to what is the doctrine and practice of the Peruvians as to the use of this vegetable, I must introduce the subject with a summary of what has been written about it by the historians of Peru and by travellers in that country. The accounts which have thus appeared—from time to time are apparently very contradictory; but I think they may be reconciled, and a consistent result obtained.
In the first place, however, let me remark that I have ventured to restore to the commercial article its original name, Cuca. This was Its Indian name, which the Spaniards corrupted into coca. But there is no reason why other nations should adopt a Spanish corruption; and there is a very good argument against transferring it to our own tongue, inasmuch as we have already two totally different vegetable products, cocoa and cacao, which, as indiscriminately pronounced in ordinary speech, coco and coca, are undistinguishable from the corrupt name of this new invention. I hope, therefore, that others will second me in attaching a characteristic name to an article which seems very likely to come ere long into general use among our countrymen at home.
The early historians of Peru have taken special notice of the culture, properties, and uses of Cuca. Among these, none is more full, clear, and fair, than the famous chronicler of the reign of the Incas and of the Spanish conquest, Garcilasso de la Vega. His narrative bears internal evidence of great historical care. Other reasons, to be alluded to presently, also add to the confidence which the statements themselves create in the reader; and hence it is scarcely necessary to refer to any other early authority. Garcilasso’s information was derived partly from what he personally knew, partly from a Spanish priest, Blas Valera, who was long in Peru, and whose manuscripts came into the historian’s possession.
De la Vega informs us that the use of Cuca in Peru dates from an early period of the dominion of the Incas; that at first it was scarce, and was monopolised by the monarchs themselves; that it was employed as an offering to the sun, their parent and deity; and that sometimes, however, a basket of it was presented to one of their curacas, or lords, to whom the ruler desired to show special favour. But, as the Incas extended their conquests northward along the Cordilleras of the Andes, the culture of the plant also became much more widely extended, through the acquisition of suitable lands for the purpose; the leaves came gradually into more general use; and at the time of the Spanish conquest of Peru, the natives almost universally indulged in Cuca-chewing.
The Spaniards, however, were too devoted Catholics to fall into a custom which was the offspring, and continued to have the savour, of profane heathen rites. The chewing of Cuca was detested by them, condemned by public opinion, and charged with being baneful to the health of those who gave themselves up to it. Strong prejudices thus prevailed against it. But Garcilasso de la Vega and Blas Valera protest against these prejudices, and declare that the Peruvian natives esteemed Cuca as above gold and silver in value; that it possessed great energy in preserving strength during fatiguing exercise and privation of food; that it was an useful medicine for improving the teeth, mending broken bones, curing maggoty sores, and warding off the effects of cold; and that another important purpose served by it was to enrich the Spanish traders in it, and to supply the chief tithes of the cathedral and canons of Cuzco.
The plant is described as a shrub about six feet high, much resembling in foliage the strawberry-tree of Spain (Arbutus Unedo), but producing much thinner leaves; and it is stated that the gatherers pick off the leaves individually with caution; dry them quickly in the sun, so as to retain their green colour, which is much prized; and preserve them carefully from damp, which seriously damages their quality. Garcilasso adds an anecdote which illustrates both the Spanish dislike and the real virtues of Cuca.
A Spanish friend of his met one of his countrymen, a poor soldier, plodding his solitary way among the Andes, chewing Cuca, and carrying his two-year-old child in his arms. On upbraiding the man for adopting a barbarian custom, abhorred by all true believers as the fruit and symbol of idolatrous worship, the soldier said that might be; he at one time shared in these prejudices, but had found he could not carry his child without the strength which the Cuca imparted, and was too poor to afford the cost of a bearer to relieve him of his burden. Nowhere does the author of the Royal Commentaries of the Incas say one word of any evil consequences actually resulting from the use of this vegetable becoming a habit.
In face of the opposition it received from subsequent authors, and from some modern travellers, this testimony of Garcilasso de la Vega may be received with favour. He was son of one of Pizarro’s conquering captains of the same name, by a niece of one of the last of the Incas. He would, therefore, escape the tendency of the pure Spanish race to vilify the manners and customs of the people they had subdued; and his native and royal extraction gave him access to full information on such a subject. It is true that he left the land of his birth at the age of twenty (in 1550), and passed the remainder of a long life in Spain. But a youth of his family extraction on both sides was old enough to take part in the stirring events of the period while he remained at Cuzco; and, after leaving it for Spain, he kept up correspondence with the friends he left behind him, collecting from them information for his history.
I was first led to pay attention to the Peruvian custom of chewing Cuca by reading, full forty years ago, the Travels in Chilé, Peru, and on the River Amazons, of the German naturalist Pöppig, who has taken a very different view of this national custom from Garcilasso de la Vega and Blas Valera.
Pöppig was no less than five years in these regions, from 1827 to 1832, and passed much of his time among the Cuca-chewers in the forest regions of the Peruvian Andes. Probably no European in the present century had such opportunities of intimately studying the habit. His statements of fact and his opinions are, therefore, entitled to much consideration.
The conclusion at which he arrived is that “The habit is as seductive and as injurious to health, mind, and morals as that of tippling in Europe, or opium-eating in the East. He says it is almost confined to natives of the aboriginal red race, has not been adopted by negroes, and is discountenanced among all of European descent; that even those who use it to no great excess must stop their work several times a-day to chew their quid contemplatively, and are much displeased if disturbed in their placid enjoyment; and that those who have got thus far are apt to become mere slaves to it, surrender every other occupation for it, and, quitting society, pass their time in the wild forests between hunting for their sustenance and lying under a tree chewing their beloved weed, calling up delightful visions and building castles in the air, and so insensible to outward occurrences as to remain thus all night indifferent to cold, torrents of rain, and even the howlings of the panther in their neighbourhood.”
“But, in the end, the stomach gives way; the countenance becomes haggard, and the limbs emaciated; they can no longer take sufficient food, and even lose all relish for the enjoyment which has been insidiously destroying them; constipation sets in, even obstruction of the bowels ensues, or jaundice, or dropsy; and thus at last life is cut short about the age of fifty by one or other of these maladies, or through simple extenuation and exhaustion. Sometimes, when a fit of excess is followed by dislike, and the habit is suddenly abandoned, the sufferer rallies, and seems about to be reclaimed. But, ere long, like the drink-craver in exactly the same circumstances, he is driven by an uncontrollable impulse to further and worse indulgence.”
“When the habit has thus degenerated into a vice, the victim becomes, in the language of the country, a Coquero, and is irreclaimable. If a man of Spanish blood begin to use Cuca, he is at once looked on with suspicion; for usually, in the course of time, he abandons himself entirely to it, and becomes an outcast from the society in which he moved.”
Pöppig gives, among other instances, a melancholy tale of a young man of good station in Huanuco, who fell into this vice, lived for some time the life of a savage. in the woods, was found out by his relatives in a miserable condition in a remote native village, and was brought back to town by force, and for a short time apparently reclaimed. But at length, eluding his friends, he fled back again to the mountains, and resumed the habits of a confirmed Coquero.
It is unnecessary to follow Pöppig further through the arguments and illustrations, very interesting however, by which he was led to denounce Cuca as a deceitful and destructive stimulant of the narcotic kind. He allows, nevertheless, that it has really wonderful power in supporting the strength under prolonged fatigue without food. He mentions that, in his long rides through the Peruvian forests, he had seen his Indian followers accompany him on foot for fifty miles in one day, without food, or anything else except Cuca; and that, in the revolutionary wars which ended with the Spanish American States throwing off subjection to old Spain, the native Peruvian troops, poorly clothed and ill fed, were able to fall upon their enemies by surprise, by making long marches among the mountains without food or sleep, merely resting for intervals of a few minutes occasionally to refresh themselves by Cuca chewing.
He adds an important fact, which I am able to confirm, that, when his day’s journey came to an end, he did not find his Indian attendants had at all lost their appetites; for, when done with work for the day, although they did not care for food while travelling and chewing, they made an excellent meal in the evening, usually eating twice as much as satisfied his own hunger. These last rather inviting statements will prepare the way for the more favourable testimony of ulterior travellers on the same subject.
Three valuable observers, who have since spent some time as naturalists in Peru and became familiar with the fondness of the natives for the Cuca-leaf, have treated the question minutely; and they separately bear witness to the soundness of the views of Garcilasso de la Vega and Blas Valera, and to some mistake on the part of Pöppig, for which it is not easy to account. It is important to see to what their testimony exactly amounts. It is by no means sufficient, as some have thought, to set aside Pöppig ‘s statements, by referring to the wide dissemination of the Peruvian habit. It has been said, indeed, to be nearly universal among a population of eight million inhabiting the Andes; and the annual collection of the leaf has been estimated at no less than thirty millions of pounds. Witt the habit of intoxication with opium, or with alcoholic spirits, might be upheld on the very same plea.
In 1838, Von Tschudi visited Peru, and was for some time in the neighbourhood of Lima, as well as in various other districts, where the natives of Indian race almost universally use Cuca, and where he himself repeatedly made trial of it.
Dr. Veddell of Poitiers, who had previously investigated with singular success in Upper Peru the botany of the cinchonas, and was the first to discover there the true yellow bark tree, the most valuable of them all, revisited Bolivia in 1851, where, in the province of Yungas, the finest Cuca is said to be cultivated. He, too, made trial of it himself, and had very ample opportunities of witnessing its use and its effects among the Peruvians.
In 1860, Clements Markham, who had charge of the Government expeditions to Peru in quest of cinchona plants for cultivation in India, was much in the wildest forest districts of Lower Peru, immediately adjoining Bolivia, was always attended by Cuca-chewing natives, and not unfrequently followed their example.
All these authorities, undeniably of the first rank, agree that the repulsive accounts of Pöppig are much exaggerated. The general result of their experience is to raise a suspicion that, in a few instances, his deplorable history of the abandoned irreclaimable Coquero may be not far from the truth. But they do not seem to have themselves met with any such cases.
Von Tschudi, indeed, says, that a profligate Coquero may be known by his foul breath, stumpy teeth, pale quivering lips, black-cornered mouth, dim eyes, yellow skin, unsteady gait, and general apathy; but in his narrative, obviously in part compiled, he does not say he described such a man from actual observation; on the contrary, all three travellers represent in colours more or less strong the great utility of Cuca to the Indians in the hard labour they have to undergo.
Von Tschudi observes that, in his own trials, he found it to be a preventive of that difficulty in breathing which is felt in the rapid ascent of the Andes; that, when frequenting the Peruvian Puna, or great desert table-land, 14,000 feet above the level of the sea, a decoction of the leaves enabled him to climb heights, and pursue swift-footed game, with no greater difficulty than in similar rapid exercise on the coast ; and that he experienced a sense of satiety which did not leave him till the time of the next meal after that which he ought otherwise to have taken. He mentions the following instance, which he carefully watched, of the power of the Indians to bear long fatigue without any other sustenance.
A miner, sixty-two years old, worked for him at laborious digging five days and nights without food, or more than two hours of sleep nightly, his only support being half an ounce of Cuca leaves every three hours. The man then accompanied him on foot during a ride of sixty miles in two days; and, at parting, expressed himself ready to engage to undertake as much as he had performed. Nevertheless, von Tschudi was assured by the priest of the district that he had never known the man to be ill.
In general terms, this traveller declares he is clearly of opinion that the moderate use of Cuca not only is innocuous, but may even be conducive to health and, again he observes,”… after long and attentive observation, I am convinced that its use in moderation is nowise detrimental, and that without it the poorly fed Peruvian Indian would be incapable of going through his usual labour. The Cuca plant must be considered a great blessing to Peru”
Weddell, in less glowing terms, says, that careful inquiry where Cuca is most in use satisfied him that it might be injurious to Europeans not gradually accustomed to it; but that it has the power of sustaining the strength for a time without food, yet without interfering with the appetite soon afterwards; that, in his own trials, he experienced a slight excitement and a little subsequent sleeplessness, but nothing else; and that, in the countries he visited, he never saw things go the length described by Pöppig, who must have been misled by exceptional cases
The testimony of Clements Markham is very explicit. He says the properties of Cuca are to enable a greater amount of fatigue to be borne with less nourishment and to prevent difficult breathing in the ascent of steep mountain-sides; that, although when used to excess it is prejudicial to the health, yet ” … of all the narcotics used by man, it is the least injurious and most soothing and invigorating” ; that he chewed it frequently, and, besides an agreeable soothing feeling, found he could endure long abstinence from food with less inconvenience than he could otherwise have felt; and that it enabled him to ascend precipitous mountain-sides with a feeling of lightness and elasticity, and without losing breath. ” It enabled him to ascend the mighty passes of the Andes “… with ease and comfort.”
It is difficult to reconcile with these favourable opinions the very opposite conclusions of Pöppig, founded apparently on personal observation. Probably, he was too prepossessed with the abhorrence with which the practice of chewing Cuca was regarded by the white inhabitants of the towns; hence he might have mistaken for the effects of the habit what perhaps was no more than the physical expression of the natural indolence of the Indian race when indulged in to excess; or, in other cases, the result of over-indulgence in ardent spirits, which, he says, the Coquero sometimes adds to his other vices.
Mr. Bates met with this habit among the natives on the banks or the river Amazons, where he says it is regarded with abhorrence by respectable people, and therefore only practised secretly. He represents Cuca, there called ypaaå, as stimulating and not injurious when used in moderation, but producing weakness and nervous exhaustion when indulged in to excess. His observations, however, are too brief and general to throw much light on the subject.
The shrub which produces Cuca thrives best in the clearances in the elevated forests of the Andes, in a climate distinguished by frequent rain-showers, and exemption equally from frosts and from extreme heats. In due season it is covered with clusters (fascicles) of delicate white flowers, which give it the appearance of our blackthorn in spring; and the flowers are succeeded by red berries. The plants bear stripping of their leaves three times in the course of the year. Great care is usually taken to nip them off without hurting the axillary buds. They are dried at once quickly and thoroughly, and so as not to curl; at least, all good specimens I have seen present the leaves flattened and many of them entire, almost as if intended as a herbarium.
Great care is taken to keep them afterwards dry, when transported from place to place. When newly dried, they have a strong odour, which is said to be apt to cause headache in those frequent the drying-floors for the first time; but this odour passes off by the time the leaves are packed. The packages when opened have a powerful tea-like odour; which they retain on reaching Europe, if duly protected from damp. In Peru it is alleged that their properties soon deteriorate, that in a few months they lose much of their virtue, and that when taken to the coast they are worthless in twelve months. This statement, however, must be received with some limitation.
It is evident, from the pains taken in Peru to preserve them from damp and exposure, that the leaves are easily damaged without due precaution; so that neglect will account for the inferiority of many old samples. Besides, it is contrary to all analogy, that leaves destitute of volatile oil, at least not owing their virtue to volatile oil, should lose them under careful preservation from the ordinary causes of decay; and various medicinal leaves of European growth, formerly thought to become inert by keeping, are now, known to retain their properties very long, since we have been aware of the precautions for preserving them. Further, specimens brought to Europe have been found to yield a crystalline principle, which physiologically possesses no mean activity as a narcotic, which is probably the active ingredient, and which apparently bears transport and long keeping well. Lastly, well preserved Cuca will produce in Europe in no small degree, after being kept several years, the remarkable effects on man which are every day experienced in Peru.
Cuca is not yet a regular commercial article in this country. In the prospect of its soon becoming so, the characters of a good sample should be well understood. I have had two fine specimens of it, and have seen several evidently much inferior. The fine qualities consist of leaves in a great measure unbroken, often folded, but many of thein too spread out, never curled, but always flattened, never brown, always deep green on their upper and gray-green on their under source, and uniform in that respect, seldom mottled in colour. They are thin and crisp, beautifully reticulated, and traversed longitudinally by a single fine vein on each side of the strong midrib. In mass they have a strong odour resembling that of tea, and when chewed they have a peculiar well-marked herbaceous taste, not disagreeable, followed, after a continuous chewing for some minutes by a gentle, pleasant sense of warmth in the mouth. Inferior specimens, besides differing in appearance from these, have a fainter odour, and do not occasion warmth in the mouth when chewed.
Cuca has been subjected to chemical analysis, and found to contain a crystalline principle, to which naturally has been given the name of cocaine. But it is not my intention to enter here into the chemistry of the subject.
Nor is the Botanical Society the fit place for discussing fully the experimental investigations which have been made into the physiological actions of cocaine, or of coca itself, further than as they bear on what has been said above upon that point, or on what is to follow as the account of my own observations. In that respect, the most important inquiry is that of Dr. Mantegazza of Milan, published in a prize essay, which has been noticed in the Őesterreichischce Zeitschrift fűr Praktische Heilkunde for November 1859.
He found, by personal trials, that in small doses it promotes digestion, increases the frequency of the pulse, raises the animal heat, and accelerates respiration; that in a dose somewhat larger, there is added a facility of motion and desire for it, succeeded by a soothing effect; and that in a large dose, such as three drachms or upwards, it doubles the rate of the pulse, causes flashes of light, headache, strong tendency to muscular action, and great vigour of mind, succeeded by a state of pleasing, imaginative calm, described by him in brilliant colours, which resemble the poetical ravings of De Quincey, in representing the visionary musings of the opium-eater.
A specimen of the plant is now in flower in the Edinburgh Botanic Garden (April 18th). It is well represented in an uncoloured engraving in Hooker’s Companion to the Botanical Magazine, ii, 25, 1836.
Were these effects the general rule, there would be more justice in the unfavourable representations of Pöppig than has been hitherto admitted. It must be allowed as some confirmation of Mantegazza’s statement, that Weddell thought he occasionally observed hallucinations in the Coqueros of Peru, when under the influence of their dose; and that Von Tschudi saw effects which disposed him to compare Cuca with stramonium, an unequivocal narcotic poison. I scarcely think the recently ascertained deadly effects of the principle cocaine upon animals can be fairly added to the evidence in the same direction. It is true that experimental inquiries, and, among these, the most recent by Dr. Alexander Bennett, published in his thesis, and also as part of an experimental research carried on by a committee of the British Medical Association, prove that in small animals cocaine produces in an adequate dose paralysis of sensation, tetanic convulsions, and death. But he found the same effects to be caused by theine, caffeine, theobromine, and guaranine, the nearly identical crystalline principles of tea, coffee, chocolate, and the Brazilian guaranå; yet no one will imagine on that account, that the habitual use of these restoratives has any injurious influence on the health.
At all events, however, the following experiments, with doses little short of those which are stated to have acted so extraordinarily in the case of Dr, Mantegazza, show results materially different from his, and prove that the leaves may be easily used by most, if not all, persons, so as to produce no unpleasant, unsafe, or even suspicious effects whatsoever. It must be acknowledged, nevertheless, from consideration of the whole facts recorded by good observers, and the opinions formed by competent judges, that, if Cuca is to be added to the restoratives of Europe—which seems not unlikely —it ought to be used at first with caution, and under close observation of its relative effect in several varieties of condition, such as age, sex, and constitution, rest and exercise, bodily and mental, dose and form, etc.
My first trials were made in 1870, when I was not aware that anyone else in Europe had experimented with it. My specimen was sent to me by a London mercantile gentleman, Mr. Batchelor, six years before, and must therefore have been kept for seven years at least. The leaves had been excellently dried, flat, unbroken, and green; and they had been equally well preserved by sprinkling a little quick-lime among them before being shipped. Even in 1870 they were green, brittle, and strongly-scented. Two of my students, out of the habit of material exercise for five months, tired themselves thoroughly with a walk of sixteen miles in the month of April. They returned home at their dinner hour, having taken no food since a nine o’clock breakfast. They were very hungry, but refrained from food, and took each an infusion of two drachms of Cuca, made with the addition of five grains of carbonate of soda, which was added to imitate the Peruvian method of chewing the leaves along with a very small quantity of lime or plant ashes. I am satisfied, however, that any such addition is superfluous.
Presently hunger left them entirely, all sense of fatigue soon vanished, and they proceeded to promenade Prince’s Street for an hour; which they did with ease and pleasure. On returning home their hunger revived with great intensity; they made an excellent dinner ; they felt alert all the subsequent evening, slept soundly all night, and next morning awoke quite refreshed and active. One of them, in setting out for the evening promenade, felt very slightly giddy, as if he had taken just a little too much wine. But the other experienced no other sensation than the removal of fatigue, and ability for active exertion.
Having subsequently received from Dr. Alexander Bennett a larger supply, obtained by him in Paris, I made farther trials in the spring of last year, 1875. This sample was more broken, less green, less scented than the other, less strong in taste, and scarcely producing any sense of warmth in the mouth when chewed. Obviously it was of lower quality. Ten of our students made trial of it under conditions precisely similar to those observed in the prior experiment; and they reported the results to me severally in writing. Their walks varied between twenty and thirty miles, and three cleared the latter distance on a rather hilly road at nearly mile pace over all. Two were unable to remark any distinct effect from the Cuca. Several felt decided, but only moderate relief from fatigue. Four experienced complete relief, like their predecessors in 1870; and one of these had walked thirty miles without any food. All found their hunger cease for a time; but shortly afterwards neither appetite nor digestion was at all impaired. No disagreeable effect was produced at the time or subsequently, except that a few felt a brief nausea after their dose, owing probably to the form of infusion in which it was taken.
I then determined to make some careful personal trials with the scanty remains of my best specimen. For this purpose I thought it best to adopt the Peruvian method of chewing, but I discarded their lime and ashes. For not only was I unable to discover, in the nature, composition, or effects of the leaf, any chemical or physiological reason for such addition; but likewise I found that the Llipta, as the addition is called, which was presented to me with one of my specimens from Peru, has no alkaline or calcareous taste, and therefore cannot effect decomposition of the leaf while it is masticated. The result confirms the view I had thus taken.
I had first to ascertain what amount of exercise was required to cause very thorough and permanent fatigue. At the same time, I made such observations on certain of the functions as seemed desirable and easily practicable. In the beginning of May, under a day temperature of 58 degrees , I walked fifteen miles in four stages, with intervals of half-an hour, at four-mile pace, without food or drink, after breakfast at half-past eight, and ending with a stage of six miles at half-past five in the afternoon. I had great difficulty in maintaining my pace through weariness towards the close, and was as effectually tired out as I remember ever to have been in my life, even after thirty miles at a stretch forty or fifty years before. Perspiration was profuse during every stage, particularly the last of all. I took the urine-solids every two hours, and found a decided increase of the hourly solids during the forenoon’s exercise, and a decrease during the evening’s rest after dinner. The pulse, naturally 62 at rest, was 110 on my arrival at home; and two hours later it was still 90. I was unfit for mental work in the evening, but slept soundly all night, and awoke next morning somewhat wearied and disinclined for active exercise, although otherwise quite well. Two days afterwards, I repeated this experiment, and obtained precisely the same results, except that the urine-solids were not so abundant during exercise as before, although my food had been precisely the same.
Four days later, with precisely the same dietary, I walked sixteen miles in three stages of four, six, and six miles, with one interval of half-an-hour, and a second of an hour and a-half. During the last forty-five minutes of the second rest I chewed thoroughly eighty grains of my best specimen of Cuca, reserving forty grains more for use during the last stage. To make assurance double sure, I swallowed the exhausted fibre, which was my only difficulty. On completing the previous ten miles, I was fagged enough to look forward to the remaining six miles with considerable reluctance. I did not observe any sensible effect from the Cuca till I got out of doors, and put on my usual pace; when at once I was surprised to find that all sense of weariness had entirely fled, and that I could proceed not only with ease, but even with elasticity. I got over the six miles in an hour and a-half without difficulty, found it easy when done to get up a four-and-a-half mile pace, and to ascend quickly two steps at a time to my dressing-room, two floors upstairs; in short, had no sense of fatigue or other uneasiness whatsoever. During the last stage, I perspired as profusely as during the two previous walks.
On arrival at home, the pulse was 90, and in two hours had fallen to 72 ; the excitement of the circulation being thus much less, and its subsidence more rapid, than after the same amount of exercise without Cuca. The urine-solids hourly were much the same while the exercise lasted as during exercise on the day of fifteen miles’ walking without Cuca, although the breakfast dietary was precisely the same. During the evenings rest, the urine-solids were almost the same as during the preceding period of exercise—a fact which is capable of more interpretations than one.
On arriving at home before dinner, I felt neither hunger nor thirst after complete abstinence from food and drink of every kind for nine hours; but on dinner appearing in half an hour, ample justice was done to it. Throughout the evening I was alert, and free from all drowsiness. Two hours of restlessness on going to bed I ascribed to the dose of two drachms being rather large; and after that I slept soundly, and awoke in the morning quite refreshed, and free from all sense of fatigue, and from all other uneasiness. Another effect, not unworthy of notice, was that a tenderness of the eyes, which for some years has rendered continuous reading a somewhat painful effort, was very much mitigated during all the evening.
I reserved what remained of my good specimen of Cuca for further trial during my autumn holidays in the country. On September 15th, while residing at St. Fillans on Loch Earn, I ascended Ben Vorlich. The mountain is 3, 224 feet above the sea, and 2,900 feet above the highway on the loch-side. The ascent is for the most part easy, over first a rugged footpath, and then through short heather and short deep grass; but the final dome of 700 feet is very steep, and half of it among blocks and slabs of mica-slate, the abode of a few ptarmigan, of which a small covey was sprung in crossing the stony part. On the whole, no Highland mountain of the same height is more easily ascended. The temperature at the side of the lake was 62 degrees ; on the summit, 52 degrees. In consequence of misdirection, I had to descend an intervening slope on the way, so that the whole ascent was 3,000 feet perpendicular. I took two hours and a half to reach the summit, anl was so fatigued near the close, that it required considerable determination to persevere during the last 300 feet. I was richly rewarded, however, by an extremely clear atmosphere, and a magnificent mountainous panorama, of which the grandest object was Ben-Nevis, forty miles off, shown quite apart from other mountains, and presenting the whole of its great precipice edgeways to the eye. My companions, who, as well as I, were provided with an excellent luncheon, soon disposed of it satisfactorily; but I contented myself with chewing two-thirds of one drachm of Cuca leaves.
We spent three-quarters of an hour at the top, during which I looked forward to the descent with no little distrust. On rising to commence it, however, although I had not previously experienced any sensible change, I at once felt that all fatigue was gone, and I went down the long descent with an ease like that which I used to enjoy in my mountainous rambles in my youth. At the bottom, I was neither weary, nor hungry, nor thirsty, and felt as if I could easily walk home four miles; but that was unnecessary. On arriving home at five o’clock, I still felt no fatigue, hunger, or thirst. At six, however, I made a very good dinner. During the subsequent evening, I was disposed to be busy, and not drowsy; and sound sleep during the night left me in the morning refreshed and ready for another day’s exercise. I had taken neither food nor drink of any kind after breakfasting at half-past eight in the morning; but I continued to chew my Cuca till I finished the sixty grains when halfway down the mountain. I had not with me in the country any apparatus for observations on the renal secretion.
Eight days afterwards, I repeated the experiment, but used ninety grains of Cuca. Being better acquainted with the way, no ground was lost by any intervening descent, so that the perpendicular height to be reached from the highway was 2,900 feet. I took two hours and a quarter to ascend, and on reaching the summit was extremely fatigued. The weather had changed, so that the temperature, 51 degrees at the loch-side, was 41 degrees at the top. A moderate breeze consequently caused so much chilliness that my party were glad to re-descend in half an hour, by which time I had consumed two-thirds of the Cuca, taking, as formerly, neither food nor drink. The effects were precisely the same, perhaps even more complete, for I easily made the descent without a halt in an hour and a quarter, covering at least four miles of rugged ground; and I walked homewards two miles of a smooth level road to meet my carriage. I then felt tired, because nearly three hours had elapsed since I consumed the Cuca, and in that time the Peruvians find it necessary to renew their restorative. But there was no more Cuca left, and I was tempted to substitute a draught of excellent porter. I suppose this indulgence led on to the unusual allowance of four glasses of wine during dinner, instead of one or none; and the two errors together, with possibly some discordance between Cuca and alcohol, were the probable cause of a restless feverish slumber during the early part of the night; but quiet sleep succeeded and I awoke quite refreshed and active next morning.
One of my sons, who accompanied me on both occasions, used Cuca the first time, but also took luncheon on the summit. Though not in good condition for such work, he made it out without fatigue; and on the second occasion, when there was no more Cuca to give him, he felt decidedly the want of it when he reached the highway at the foot of the mountain.
These trials have been described particularly, because I feel that„ without details, the general results, which may be now summarized, would scarcely carry conviction with them. These are the following. The chewing of Cuca removes extreme fatigue, and prevents it. Hunger and thirst are suspended; but eventually appetite and digestion are unaffected. No injury whatever is sustained at the time, or subsequently in occasional trials; but I can say nothing of what may or may not happen if it be used habitually. From sixty to ninety grains are sufficient for one trial; but some persons either require more, or are constitutionally proof against its restorative action. It has no effect on the mental faculties, so far as my own trials and other observations go, except liberating them from the dullness and drowsiness. which follow great bodily fatigue. I do not yet know its effect on mental fatigue purely. As to the several functions, it reduces the effect of severe protracted exercise in accelerating the pulse. It increases the saliva, which, however, may be no more than the effect of mastication. It does not diminish the perspiration, so far as I can judge. It probably lessens the hourly secretion of urine-solids. On this point I cannot yet speak with any confidence, because it appears to me that the investigation of the action of Paratriptics, or those substances which seem to lessen the wear and tear of the textures of the body in the exercise of their several functions, involves considerations and precautions which have escaped the attention of experimentalists on this interesting question, and which my own experiments hitherto have not taken completely into account.
I have made no trials of the influence of Cuca on disease, or the consequences of disease. Some notices in the journals on this subject show that it is attracting attention ; but, so far as I see, it is a difficult one, and may prove extensive, and therefore it ought to fall into the hands of some able inquirer, who will be in no hurry to rush into print. I have been asked by correspondents in the south of England if Cuca will do good to a weak heart, to an old paralysis, to the feebleness of advancing age, etc. My reply has been, that I know nothing of all this, and that no one should use it medicinally, but under the advice and observation of his medical attendant.
A more convenient form for use than that of a quid is very desirable. M. Laumaillé, who rode, or on very bad roads led, his bicycle 760 miles from Paris to Vienna in little more than twelve days, in the month of October, carried with him, as part of his scanty baggage, a small supply of the liqueur de coca, an Indian tonic, by which he was always able to assuage the sudden and painful hunger which sometimes accompanies continued exertion”
Unfortunately, he gives us too little of his experience with it ; but he observes that, when about sixty miles from Vienna, ” continuing his way along a road of fluid mire, fatigue and sleep at length told upon him, but the marvelous liqueur de coca again supported him and gave him strength”. I have made by rule of thumb a very palatable liqueur, with only a fourth of rectified spirit, and containing in half-an-ounce the soluble part of sixty grains of leaves, but I have not yet tested its virtue. Pharmaceutical chemists, however, will soon solve this problem, and, it may be hoped, without looking for a patent.
First, A Short Summary:
- Researchers are “just discovering” that Cannabis can control Epileptic seizures (Most recent New England Journal of Medicine)
- Researchers have not yet looked at Cannabis for use in Dementia/Alzheimer’s, even though seizures are common and are a leading cause of death in Dementia/Alzheimer’s. (Update 6/19/17) – this has just changed – see this on a new German-Israeli study)
- Maybe that’s because while Congress has committed some $5.4 billion this fiscal year to cancer research, about $1.2 billion to heart disease and $3 billion to research on HIV/AIDS, research funding for Alzheimer’s is “only” $566 million. Clearly that’s just not enough for researchers (mostly Big Pharma employees) to look into Cannabis as a treatment.
- On a related note, California researchers have just shown that a sleeping sickness drug developed in 1916 can reverse Autism in children; unfortunately, the test group was only 10 kids, and 5 of them were given placebos, and the researchers had to go $500,000 into debt to run the study. Evidently kids with Autism aren’t a big enough deal for Congress. Thoughtful of those researchers to care enough to go ahead though.
- And to wrap all this up in a neat little package, I figure it would cost well under $100,000 to show that Coca Leaf can not only control Epileptic seizures (as already well-known and demonstrated in 1881), but probably also Dementia/Alzheimer’s seizures – not even a diagnosed disease in 1881.
- So, a drug from 1916 is now “discovered” to cure Autism, after decades of high-dollar research into “new” cures. And Cannabis is discovered to cure Epilepsy, after more decades of research into “new” cures. And an 1881 proven cure for both epilepsy and likely for Dementia/Alzheimers, among many other killer diseases, is illegal. Go figure.
The Full Story
For several years researchers have been zeroing in on Cannabis as a source for potent medicines in treating & preventing epileptic and other kinds of seizures. The latest findings, published May 25, 2017 in the New England Journal of Medicine, showed that @ 40% of those treated with a CBD-based medicine experienced dramatic improvement in seizure intensity and frequency.
So, let’s put this together with an interesting association between seizures and Dementia/Alzheimer’s. There is plenty of research on this association. Here’s just one example.
“Of the degenerative disorders, Alzheimer’s dementia and amyloid angiopathy are known major causes of seizures. Advanced Alzheimer’s disease has been identified as a risk factor for new-onset generalized tonic-clonic seizures in older adults. It is associated with a 10 percent prevalence of seizures, particularly late in the illness. An increased prevalence of seizures also has been documented with other types of dementia.
So I suppose that it would make sense to investigate whether Cannabis-derived medicines, or perhaps the right strain of Cannabis itself, could be useful in controlling or preventing seizures in Dementia/Alzheimer’s, especially in late-stages of the disease when seizures are a known killer.
I’m sure that researchers are already drafting multi-million dollar grants to study exactly that.
So far, so good. In spite of decades of “Killer Weed” propaganda it looks like scientific minds are finally rising above the lies and finding that, consistent with centuries of well-established knowledge, the natural medicine Cannabis can be helpful in dealing with killer seizures better and with less risk of harm than pharmaceuticals.
But wait! If centuries of medical knowledge regarding the efficacy and safety of Cannabis are now appearing as “new findings” in prestigious medical journals, why not take a look at centuries of medical knowledge regarding the safety and efficacy of Coca Leaf in the same area?
Hmmmm. Could it be that a cup or two of Coca Leaf tea a day might be helpful to people with Dementia/Alzheimer’s – at least in preventing seizures, if not in other ways too. Let’s see. Who would know?
Well, there is a little book entitled “Erythroxylon Coca”, written by By W.S. Searle, MD and published in New York in 1881. (Dr. Searles book is included in its entirety in my ebook “Coca Leaf Papers” available on the sidebar of this post.)
Dr. Searles book is only one of many in which the use of Coca to treat and cure epileptic seizures is covered, but here is what Dr. Searles had to say:
“Coca Leaf & Acute Disease”
“The relations of Coca to acute disease are extremely important. As a physician, I would not be without it under any consideration. How thoroughly will every physician, understand me when I say that we are not seldom compelled to stand by and witness the death of patients who are really better of the disease which destroys them than perhaps at any previous time during their sickness. We are unable to support them, and they die from exhaustion of the vital forces.”
“But in Coca we have a powerful agent, whose disturbing influence over physiological processes is so little felt that it neither interferes with recovery from disease by natural course, nor with the action of remedies. And its sustaining power is so marvelous, that I prophesy that by its help we shall hereafter be able to cure many cases of disease which were otherwise hopeless.”
“I am informed by my colleague, Dr. John L. Moffat, of Brooklyn, that he has had very encouraging results from the use of Coca in hay fever in four instances. Of course, its action here is antipathic, or rather, it probably acts simply by its sustaining power, and by its antipathic relations to asthma. But even an efficient palliative, which can do no harm, will be welcomed by those who are annually visited by this plague.”
“It has been affirmed by some English authorities that Coca is valueless in epilepsy. For myself I can report that, in one instance of the fully-fledged disease, occurring in a middle-aged lady, but in whom the paroxysms did not recur oftener than once in six months, an apparent cure has been effected by means of Coca alone. She has now passed eighteen months without a seizure. I have also more striking reports from some of the members of this society, who report very marked results in several severe cases which would yield to no other remedy.”
“It is too early yet, however, to claim for Coca really curative powers in this terrible disease, which has so long been an “opprobrium medicorum”. Still, it is highly probable that the forms of it used by the English physicians in their trials were inert. This is rendered more than likely by the fact that one of the most expert chemists of New York City carefully searched both France and England during the summer of 1880 for good Coca, and was unable to obtain a single valuable specimen.”
“In view of the fact that all the drugs now ranked as anti-epileptic by the allopathic school of medicine are so injurious to the general health, and in view of the results attained by myself and my colleagues, imperfect as yet though they are, I earnestly urge the faithful trial of Coca in epilepsy.”
Well, about 140 years have passed and where are those “faithful trials” of Coca Leaf for Epilepsy – and incidentally for Dementia/Alzheimer’s, Congestive Heart Failure, Diabetes, Obesity, and a couple of dozen other killer diseases? Nowhere in sight.
Researchers with Ph.D’s and major institutions behind them are getting tens of millions of dollars to “study” Dementia/Alzheimer’s, but not a peep out of the research establishment about Coca Leaf Tea. And, of course, since I’m not in the club I can’t get a grant, even though I could pretty much prove or disprove the efficacy and safety of Coca leaf for Dementia/Alzheimer’s with a few thousand bucks. But as noted, I don’t have a Ph.D. and I’m not a member of the club, so no institution gives a shit what I say.
Hell, maybe I’ll just do a GoFundMe request for a couple of tickets to Bolivia, grab a hundred kilos or so of fresh Coca Leaf, and come home and start handing out Coca Leaf Tea at a church social or two, and maybe a local nursing home. Think I would get past US Customs/DEA? Might actually be a great idea – let them bust me for trying to bring Coca Leaf in for Dementia/Alzheimer’s patients.
I wonder how many members of the US Congress, who make the laws forbidding Coca Leaf coming into the US, have someone in their family with Dementia/Alzheimer’s. (I’m resisting the obvious snide remark here because while it might be accurate it would also be cruel.)
Anyone have any suggestions?
The range of diseases and conditions that were successfully treated and cured by European and US physicians using Coca Leaf over the course of hundreds of years should be truly amazing to us in the 21st Century, even those of us who have been propagandized into believing that allopathic medicine and modern science have “made great strides”, “revolutionized the treatment of disease”, yada yada.
As you look over the table below you might reflect on how little actual progress has been made in the treatment and cure of so many diseases, although we have certainly developed a lot of impressive technology and there have been some dramatic, if somewhat mixed-blessing advances such as antibiotics.
However, let me point to just one example; with all of our vaunted antibiotic technology huge numbers of people still die of Pneumonia – a deadly condition that doctors of the 18th and 19th centuries who were familiar with Coca leaf (and who didn’t resort to poisonous ‘remedies’ like Mercury, Arsenic and Bleeding) were quite often able to treat and reverse successfully with a few cups a day of Coca Leaf tea.
Also, since many of today’s most destructive diseases did not exist, or didn’t have a name during those earlier centuries, this post is intended to point to the historical record that strongly suggests that if pure, natural Coca Leaf were freely available today as a natural medicine it could lift the immense burden of these modern conditions and diseases from tens of millions of people virtually overnight, with no “side effects”, no risk, and for literally pennies a day.
Freely available Coca Leaf would literally destroy the market for useless, often even dangerous pharmaceuticals as well as the incredibly lucrative market for America’s beloved over-the-counter “remedies” – which, of course, would guarantee strident howls of objection and opposition. Americans spend $625 Billion a year on the over 300,000 “Over The Counter” medicines that promise relief from pain and suffering of all kinds.
Here is a table taken largely from the work of Dr. Golden, whose “History of Coca” (1901) outlines the conditions and diseases that were known in the 1800’s to be treatable and curable by Coca Leaf, along with number of diseases and conditions that have been largely ‘discovered’ in the century since Dr. Golden wrote. I believe that the evidence that he and other physicians and scientists recorded in their times shows that simple natural Coca Leaf infusions and extracts could prevent, treat and perhaps cure these modern diseases and conditions where the products of “Pig Pharma” so often fail.
Please consider the physical, emotional, spiritual and financial impact on the lives of millions of individuals and their families if even one or two of the conditions/diseases in the following table were proven beyond all doubt, using all of our contemporary research powers, to be either effectively treated or actually cured by drinking Coca Leaf Tea alone – no other treatments or medications needed.
And once you have reflected on this, if you are a strong advocate of legal Cannabis perhaps you’ll consider adding Coca Leaf to your demands that the US government and Pig Pharma back off and go away.
If you would like to read Dr. Golden’s extraordinary “History of Coca” I have digitized his book and it is available here. ($1.99 for the full 251 page book plus bibliography).
I have kept all of the original illustrations intact and – most importantly – I have hyperlinked as many of Dr. Golden’s bibliographic references to the original source materials as I could track down, almost all of them freely available in internet historical book archives.
Have fun – I certainly did while tracking down and studying these obscure but critically important resources for treating and healing disease using one of the most amazing natural medicines ever.
Angelo Mariani was without doubt the most successful, and probably the most ethical of all of the 19th Century manufacturers of Coca Leaf-based tonics. Unlike most other manufacturers, of which there were hundreds in Europe and the US, he practiced strict quality control, even to the point of developing proprietary Coca plantations in Peru and Bolivia where his proprietary Coca Leaf was grown, harvested, processed and shipped to Europe under carefully controlled conditions.
In contrast most other tonic manufacturers used cheap, dried-out Coca Leaf scrap that was the reject of Coca harvests in Peru and Bolivia – literally the scrapings from the Coca Leaf processing floors in those countries. And reminiscent of the Cocaine trade today these unscrupulous manufacturers didn’t hesitate to adulterate their products with whatever cheap crap they thought they could get away with to bulk out their products.
In addition, the Bordeaux wine that he used as the base and Coca solvent for his tonic was sourced from several prominent French chateau producers, whereas other manufacturers who tried to copy Mariani’s success used the cheapest red swill they could obtain. Again, exactly the kind of behavior we see in 99% of today’s Cocaine (and Heroin) markets.
As a result Mariani’s tonic delivered the same quality medication to patients from one bottle to the next, and it was also pleasant-tasting, and because of these qualities it remained the premium Coca Leaf tonic on the market for decades both in Europe and North America.
Mariani’s attention to detail, and his energetic marketing, primarily through the publication of testimonials from prominent users of his products worldwide, were responsible for his life-long success and should be studied carefully by entrepreneurs in the Medical Marijuana space today.
In this post you’ll get a sense of how doctors and patients of the late 19th Century viewed Vin Mariani tonic. As you read through these excerpts from their correspondence to Mariani you have to ask yourself – were all these people simply idiots, or were they competent physicians and completely sane patients? It follows that if they were neither insane nor idiots, then perhaps the insane idiots are those who stand in the way of sick people having access to pure, natural Coca Leaf remedies today.
These remedies are certainly available (see this post on medicinal tonics being produced in Bolivia today), and given the outstanding economic success of Medical Marijuana in those US states where it is finally legal, you have to ask yourself “What are we waiting for? Why aren’t we growing Coca and producing Coca Leaf medicines in the US today?”
Here are a few of the testimonials from the files of Angelo Mariani:
Meulan, March 17, 1874.
I wish to inform you that I have nothing but good results to report in all the cases in which I have employed the Vin Mariani in my practice. Yours, very respectfully,
DR. GASTOK MARCEL
Paris, May 12, 1874.
One of my patients, Lady Superior of a convent in the environs of Paris, affected with a profound anemia, which has resisted all treatment, and which, by the long use of iron and quinine, had become complicated with constipation and gastric disturbance, was relieved of the latter symptoms after twenty days’ treatment with Vin Mariani, and under the influence of this same medicine her anemia gradually lessened, and in the course of three months disappeared.
10 Rue Castiglione, Paris.
Obliged by professional duties to be continually near sick people, who often do not leave me time to take my meals, I desired to experiment with Coca as an analeptic. My trials have been with Vin Mariani. and here is what I have found :
A Bordeaux-glass full of this wine has always sufficed to make me forget hunger and to sustain my strength. I felt a slight warmth and general toning up of the body; the digestion of the meal which followed was always more easy than when I had not taken the Mariani Wine, and, although I had not a sensation of voracious hunger as I had without it, I ate very well, the stomach appearing more robust and more active.
La Porta, February 15, 1877.
Having had such splendid results in my practice with the Vin Mariani since a number of years, I counsel you to have your vrine tried in London and New York, for I am persuaded that in all the great centres, where tlio incessant occupation and the abnormal kind of life led there fatally engender anemia, Vin Mariani is able to render the greatest services.
DR. H. CONNEAU,
Member of The Academie de Médicine, formerly Chief Physician of Napoleon III. , Emperor of the French, Grand Officer of the Legion of Honor.
Paris, December, 15 1876.
Since some time I prescribe to my patients Vin Mariani, and, in the cases of gastric trouble and anemia, I have had nothing but praise for the results obtained.
M. Mariani, Paris : London.
Since using your wine my digestion is splendid and my strength is returning. Respectfully,
Paris, January 25, 1876.
M. Mariani, Paris :
“Ne pigeat ex plebeis sciseltari si quid ad curationem utile,” said Hippocrates (in prœceptis), that is to say, let us not disdain popular remedies. It was with eagerness that I welcomed in my practice the Vin Mariani, based upon Peruvian Coca, a plant so popularly used in its native place. I have proved the efficacy of your preparation, which is at the same time useful and agreeable, in cases of nervous over-excitation with sleeplessness, of uni-lateral headaches, in throat diseases accompanied with pain, in spasms of the stomach with intense thirst, and sometimes in bilious vomiting. By re-establishing the digestive functions, Vin Mariani restores the general strength of the organism, and becomes a tonic without having the inconvenience of other medicaments, called tonics, which produce constipation. As the first of all therapeutical rules is, for me, the one well known since Hippocrates, which has been newly brought forward in our days by Hahnemann, under the formula — Similia similibus curantur, I think that the efficacy of Coca, in the affections I have just enumerated, is due to the application of the homœopathic law; and the well-known fact, that the natives deceive their hunger and; calm the cravings of their stomach by chewing and swallowing a substance which habitually increases the appetite, is a confirmation of my idea.
New York, August 16, 1884.
I have prescribed the Mariani Wine extensively during the last year, and with very favorable results. Its tonic and stimulant properties are very marked, particularly as manifested in its action on the nervous and muscular systems. It is well borne by even delicate stomachs. In my experience the weaker and more delicate the subject, the more pronounced its action and the more permanent its effects. While not a universal panacea for all the ills of life, it is a very valuable therapeutic agent, and certainly possesses most of the properties claimed for it.
E. S. BATES, M.D.
161 E. 31st Street, New York.
New York, February 5, 1884.
Dear Sir : — I have examined morphologically your Mariani Wine, and also have tested it on patients, and I can cordially recommend it as being up to its standard, and of utility in cases where wine and Coca are indicated. Yours very truly,
EPHKAIM CUTTER, M.D.
Fayetteville, N. C, February 21, 1884.
Messrs. Mariani & Co., New York,
Dear Sirs : — I find Vin Mariani a most excellent – in fact, an indispensable – remedy in nervous debility. A patient of mine, a constant sufferer in this way, experiences immediate and absolute relief by the use of Mariani’s Wine, while nothing else affords him the least comfort. Your preparation of the diug cannot be too highly recommended.
Yours truly, H. W. LILLY, M.D.
London, November 9, 1882.
M. Mariani :
At the special recommendation of Dr. Lennox Browne, of London, I have tested carefully the Vin Mariani, and I recognize that its splendid effect upon the voice is extremely satisfactory, and almost instantaneous. For over two years I have tried it, ordering it to my pupils, both ladies and gentlemen, whom I had under my care for the development of the voice, and I have invariably remarked that, whenever they had any difficulty in singing or elocution, the Vin Mariani enabled them to continue the lesson, •which, without it, would have been utterly impossible. I have thus every reason to be glad that my attention was called to this remarkable preparation, and am convinced that all artists and orators will welcome it and be happy to adopt it.
PROFESSOR EMIL BEHNKE.
Fifth Avenue (near Washington Square),
New York, December 5, 188i
Messrs. Mariani & Co.,
19 E. 16th Street, New York,
Gentlemen : — Madame Valleria has desired me to state that she was greatly benefited by the using of your wine. Dr. Morell Mackenzie, of Harley Street, London, W., some years ago (three or four) recommended Madame Valleria in a similar instance to use your wine, and then, as now, she obtained instant and complete benefit from so doing, and, with compliments, I remain
Your obedient servant, R. H. PERCY HUTCHINSON.
Paris, December 2, 1880.
My Dear Sir: – Well ! yes; know it, and let me write it to you, though I have frequently told it you. Your Vin Mariani is indeed excellent, and equalled by nothing. I drink it, I absorb it, and so also does my family, and we are all deriving so much good from it that I shall never be without it. On my voice it acts like a charm. My friends and brother artists, to whom I have recommended it, drink it regularly and likewise speak in highest terms of the Vin Mariani, and I can only say I advise all artists to give it an experiment, and guarantee they will adopt its use and thank you for it, as I do with all my heart .
Of the Opera.
Dear M. Mariani : Paris, November 12, 1881.
“Your wine indeed has again saved me! Upon my arrival at the opera and just before the commencement, when I was to sing, I found I had got a severe attack of aphonia, which has disappeared as if by enchantment after I had taken slowly a glassful of your wonderful Vin Mariani. It is to be hoped that all singers will become aware of and utilize the excellent properties of your preparation.
I have tried everything, and never have found anything like it. If the government understood all its duties, it would provide a certain quantity daily for the use of our corps of lyric artists— at all events for all the pupils pf the Conservatory of Music.
Gratefully, I am yours, VICTOR CAPOUL,
Of the Opera,
Fifth Avenue Hotel
Deae Doctor : August 24, 1884
We wish to pay a tribute to the excellence of the Mariani Wine. We invariably use it during our professional labors, and find it very efficient as a tonic which strengthens the vocal organs. We never travel without it, and thank you very much for recommending us to use it. Yours, etc.,
MR. & MRS. W. J. FLORENCE.
No. 21 Fifth Avenue,
New York, December 10, 1883.
Dear Sir: – I have had occasion to speak with many of my brother-artists of the Vin Mariani. Yesterday 1 was suffering with a lowering of the voice and determined to take this wine. Well, I can assure you that it gave me im- mediate relief, and that I shall always make use of this Vin Mariani on all occasions that I have any trouble with my voice. If 1 had a singing school, I should give to my pupils, as a specific for strengthening the vocal cords, this Mariani Wine. Accept my most sincere congratulations, and believe me,
Yours faithfully, GIUSEPPE DEL PUENTE.
220 W. 38th Steeet
March 20th, 1884.
My Dear Sir: – I desire to testify to the excellent effects of the Vin Mariani. Having been for months troubled with nervous prostration, I was delighted to find the wine a most strengthening tonic. It was prescribed for me by my physician. Recommending it heartily to all who all called upon to endure the fatigues of public life, I am, dear sir,
Very sincerely yours, HENRIETTA BEEBE.
New York, July 16, 1884.
Deae Sir :— I have often wished to express to you the wonderful results produced upon my voice by the use of the Vin Mariani, prescribed by my physician eighteen months ago. During my sojourn South I had occasion to use it many times, with marvellous results; when my voice was exhausted from excessive use and so hoarse that not one word out of ten was understood, I would take a sherry glass full of the Vin Mariani and captivate my audience by my full and brilliant voice, really astonishing myself thereby. It certainly is invaluable to vocalists and elocutionists— soothing irritation of the throat, and giving strength and brilliancy to the voice. Feeling deeply grateful, I am,
Most respectfully yours, MARG. BOULIGNY.
Messrs. Maeiani & Co., New York, December 16, 1883.
Gentlemen : — I have used your wine during several years, and have found it excellent. I am well satisfied with it, and cheerfully authorize you to use my name.
Very respectfully, E. FURSCH MADI.
Mariani & Co., Mystic Bridge, Ct., August 12, 1884.
Deae Sirs :— I have taken your Wine of Coca since July 24th, as directed by my physician. I am pleased to write you that I have been greatly benefited by it. My lungs are better, and my general health is in every way improving. I can safely recommend it to my friends as the best tonic I have ever taken. My home physician is so much pleased with the effect of the wine upon me that he has already sent to you for a dozen bottles.
Respectfully yours, FANNIE S. WILLIAMS.
St. James’ Hotel
Mariani & Co., N. Y. City, February 25, 1884.
19 East 16th Street, N. Y. City,
Gentlemen: – For several years I have been using various preparations of Coca, and within the last few months, having had my attention called to your Vin Tonique Mariani, have been using it. I think it by far superior to any that I have yet seen, and I have derived great benefit from its use. Judging it from my own experience, I can and do most heartily recommend it.
Yours, etc., EMORY A. STORRS,
Mariani & Co., N. Y., August 25, 1884.
Gentlemen: — It affords me great satisfaction to give you the result of my personal experience in the use of Vin Mariani. For the past three years I have, under the direction of my physician, relied upon it in serious emergencies of illness and overwork. It sustains vitality in conditions of extreme exhaustion, and restores strength more quickly than any other tonic I have used, never causing the least unpleasant reaction.
I have tested it during long journeys, under the pressure of continued physical and mental strain, and have found it unfailing in its good effects. Frequently, when in travelling I have been unable to obtain my regular food, a small quantity of Vin Mariani has afforded me satisfactory nourishment.
I am so convinced of its beneficial nature, that I have induced many of my friends to use it, and their experience coincides with mine.
Respectfully yours, JULIET CORSON.
(The following is from the eminent Professor J. M. Carnochan, M.D., of New York, Professor of Surgery, former Surgeon-in-Chief to the State Emigrants’ Hospital, Health Officer of the Port of New York, and one of the Commissioners of the Health Department of the City of New York, etc.)
M. Mariani, Paris : New Yoek, August 29, 1884.
I have for the last eight or ten years often recommended the Vin Mariani to patients laboring under abnormal conditions of the system, re- quiring a mild tonic and stimulating influence, with marked and excellent results. For convalescents, also, I consider it a very useful remedial agent.
J. M. CARNOCHAN, M.D.
Mr.. A. Mariani, Paris, October 19, 1880.
Dear Sir : — As a rule I object to having my name used as recommending any special preparation of a drug, for this very easily and frequently leads to abuse; but I am willing to make an exception in your case, and to express at your desire, in writing, my opinion of your Wine of Coca – an opinion with which you are personally well acquainted. Since my attention has been called to the good effects of your wine by Drs. Morell Mackenzie and Lennox Browne, of London, I have tried it myself, and have observed its use by Dr. Fauvel, in his clinique and in his private practice. There can be no doubt that, properly used, it is an excellent general tonic; that it has a special beneficial action upon the digestive and respiratory organs, and that, by its stimulation of the nervo-muscular system, it enables persons to undergo physical exertions to which, without it, they would at the time not be equal, and seemingly – certainly so far as I have been able to discover – without consequent reaction of over-fatigue. The latter effect I have particularly observed, as to vocal efforts, in the cases of speakers and singers.
DR. LOUIS ELSBERG, Of New York.
19 Harley Street, Cavendish Square, W.
London, July 6th, 1885
Gentlemen: – I have much pleasure in stating that I have used the Vin Mariani for many years, and consider it a valuable stimulant, particularly serviceable in the case of vocalists.
MORELL MACKENZIE, M.D., London,
Consulting Physician to the Hospital for Diseases of the Throat; late Physician to the London Hospital.
Wiener K. K. Allgem. Krankenhaus
Vienna, July 20th, 1885. f
Messrs. Mariani & Co.
Dear Sirs : — I have used your Vin Mariani for the past three years, and have much pleasure in testifying to its many excellent qualities, combining as it does the well known constitutional effects of Cocaine with that of a mild stimulant exhibited in an acceptable form. Among the conditions in which I have found it of valuable service, I may mention in the debility occurring after prolonged illness – in Oedema of the Larynx accompanying albuminuria, in the slow convalescence after diphtheria, and especially in Graves’ disease, in which latter it not only acts as a cardiac sedative, but also diminishes the accompanying exophthalmos and laryngeal congestion.
I have the honor to be, Yours respectfully,
GEORGE W. MAJOR, B.A., M.D.,
Professor in Laryngology, McGill University, and Laryngologist and Rhinologist to Montreal General Hospital.
Saratoga Springs, July 20, 1885.
Gentlemen : — I have used the Vin Mariani in my practice quite largely for the last four years with most excellent results, and I consider it greatly superior to any other preparation in the market.
Very truly yours, CLINTON WAGNER, M.D.,
341 5th Avenue, New York.
New York, August 28th, 1883.
Gentlemen : — I have been acquainted with Mariani Wine for a considerable time, and have had occasion to recommend it frequently. I deem it a most excellent adjuvant in the class of cases to which it is recommended, and I hope in the future to still further demonstrate its usefulness.
WALTER R. GILLETTE, M.D.,
149 W. 23rd Street.
Utica, New York, July 17th, 1885.
My Dear Sirs : — I have used the Vin Mariani in many cases, and have had considerable experience with it. In my opinion it is the best preparation of Coca attainable, and can be relied upon in many conditions of debility and feeble heart action when this valuable drug is called for.
Very sincerely yours,
EDWIN HUTCHINSON, M.D.
Boston, December 15, 1884.
Messrs. Mariani & Co.: – Enclosed please find amount for two cases Vin Mariani, which please send by Adams’ Express. I use it in my own family. I have been more than pleased with its action, and consider it far ahead of any other preparation of coca, be they wines, fluid extracts, or elixirs. I have tried in my practice no less than six different preparations.
Yours very truly,
CHARLES G. BROOKS, M.D.
Hudson, New York.
Gentlemen : — Your Vin Mariani is giving excellent results. I am well pleased with its effects.
C. P. COOK, M.D., Health Officer.
New York, June 24th, 1885.
Dear Sirs: — Permit me to say that I am, and have been for years past, using your preparations of Coca, and that I fully endorse all the views that I formerly expressed about them. They are the only preparations of Coca from which I can obtain any medicinal results, and necessarily I use them exclusively, and consider your wine superior to any other makes. Many thanks are due you for your excellent preparations, and I trust others will obtain as good results from them.
Very respectfully yours,
WILLIAM H. MORSE, M.D.,
153 East 77th Street.
Gentlemen : — The “Thé Mariani” is certainly a surprising invigorator. 1 am using it with great satisfaction in debilitated subjects. Were the several fluid extracts and preparations of Coca now on the market of better grade, Coca would hold the place it deserves. Yours is the only preparation I use with confidence. Very respectfully,
H. P. BRISBANE, M.D., Health Ofiicer.
Boston, Mass., October 3rd, 1885.
Dear Sirs: – My first acquaintance with the use of Vin Mariani was made in Paris, France, in the summer of 1880, when my attention was called to it by Dr. J, Marion Sims, who recommended it as a superior tonic for nervous prostration. I have continued to use it and prescribe it ever since with entire satisfaction. I prescribe your Elixir Mariani as a brain food, and as a stimulant to the nervo-muscular system it gives immediate and lasting effect. I also have used your “Thé Mariani” in sweetened milk, and think it excel- lent. I am so convinced of the beneficial effect of these preparations that I hardly know how I could practice without them in such cases.
I am, respectfully yours,
A. W. K. NEWTON, M.D.
Brooklyn, New York, June 23rd, 1885.
Gentlemen: – As regards your preparations of Coca, it gives me pleasure to say that at the present time I can obtain none which is so satisfactory as your Vin Mariani and your Thé. I have always found same uniformly excellent and reliable. My opinion of the value of Coca in general is so well known that I need not express it.
W. S. SEARLE, M.D.
Health Department, Sanitary Bureau,
New York, October 3rd, 1885.
Mariani & Co.
Gentlemen: – I have frequently prescribed your Vin Mariani, and am familiar with its merits. I have, however, never seen any of your other preparations of Coca, and would be indebted to you for samples you so kindly offered. If they are up to the standard of your wine, you deserve to reap great rewards for devising and introducing them.
Very truly yours,
CYRUS EDSON, M.D.
New York, September 14th, 1883.
Dear Sirs: – I have used your Vin Mariani with decided benefits. Of the many preparations of Coca I find the Mariani wine the best, and I have tried many of the others. It produces an immediate tonic effect, and the improvement is lasting. I have ordered it for many of my patients, and it has not disappointed me.
Very truly yours,
S. A. FOSTER, M.D.
Augusta, Ga., January 13th, 1885.
Gentlemen: — I have been prescribing your Vin Mariaiii for some time, and with entire satisfaction. I am just recovering from an attack of diphtheria, which 1 contracted from a patient, and on account of my extreme debility I took your wine and have finished the fourth bottle, and can say I am a new creature since I commenced it, and certainly shall continue taking it for some time. Without doubt it is the greatest tonic ever made, and I am prescribing it every day.
Very truly yours.
E. C. GOODRICH, M.D.
Yonkers, New York, May 6, 1884.
Dear Sirs : — When in Paris I heard of the Vin Mariani, and the good results from using the same, particularly in the treatment of certain obscure nervous diseases. Since my return home I have advised in quite a number of these nervous cases the taking of the Vin Mariani, and with most favorable results. Am pleased to say that the Vin Mariani continues its reputation, and is growing in favor.
GEO. B. UPHAM, M.D.
Amherst, N. H., November 12th, 1884.
Gentlemen: – I had occasion many times to use the Vin Mariani in my practice, and found it the most elegant and efficacious preparation of Coca. It entirely covers and conceals the rather disagreeable taste of the drug, and in my estimation the wine itself is a most happy adjunct to the Coca, in that the alcohol therein contained quickens the absorption of it into the circulation, and, with the essential ether of the wine, adds to the strength-giving properties of the Coca. I consider that the Vin Mariani has saved my wife from sickness, which would have resulted from the breaking down of her nervous system. I have every reason to congratulate myself on the marked effect which the Vin Mariani has upon her. I am glad to recommend it as a superior preparation.
HERBERT D. HICKS, M.D.
From Columbus Medical Journal:
“Cocaine in Headache.”
We received several months ago a supply of the justly celebrated Vin Mariani, with the request that we use it personally for the relief of headache – which is the bane of our life. This wine has for its active ingredient a concentrated extract of the leaves of Erythroxylon Coca – the plant from which the new anӕsthetic is obtained. Each wine-glassful contains the equivalent of about 30 grains of the leaves. Although we have used the Vin only when we felt the attack coming on, it has uniformly aborted the attack promptly and thoroughly. We have used it with others, and with essentially the same success. We have also prescribed it as a tonic in dyspepsia and nervous prostration, and with excellent results.”— J. F. Baldwin, M.D., Editor.