The History of Coca (1901)
By Dr. William Golden Mortimer , MD
(in) The Coca Leaf Papers (2014)
By Bill Drake
In previous posts I have presented various excerpts from Dr. Mortimer’s excellent book, which not only contains a wealth of highly relevant information but illustrates the often-acknowledged but poorly understood fact that human beings keep re-discovering the insights of those gone before them, treating such “discoveries” as new knowledge.
Dr. Mortimer’s book also vividly demonstrates how easily knowledge is lost, or deliberately set aside, in pursuit of the agenda of the times.
It is impossible to estimate how many millions of people are suffering and dying right this moment because the agenda of our times has demonized Coca Leaf as part of a worldwide set of political and economic agendas conceived in ignorance and maintained with malice regarding the place of natural medicines in treating and healing diseases that arise naturally and diseases that are caused by external agents, almost always in pursuit of profit.
In both cases, access to pure, natural Coca Leaf for self-treatment would undermine the political and economic agendas of powerful groups, and so we suffer and die, by the millions each year, in servitude to these cruel and heartless sub-humans.
In my continuing protest against this overwhelming flood of power and money that is drowning the planet, I offer this excerpt from a chapter in “The History of Coca” in which Dr. Mortimer explains the place of Coca in the natural world, and the processes by which its magical properties occur. Perhaps you, the reader, will be one more voice raised against the denial of this potent natural medicine to all those suffering, dying people whose lives could be mended and saved simply by having access to this miraculous leaf.
The Place Of The Coca Leaf In The Living World
In the Coca leaf, as indeed in all plants, the cell wall is made up of cellulose, a carbohydrate substance allied to starch, with the formula xC6H10O5. The material for the building of this substance, it is presumed, is secreted by the cell contents or by a conversion of protoplasm under the influence of nitrogen. This product is deposited particle by particle inside of the wall already formed. Accompanying this growth there may occur certain changes in the physical properties of the cell as the wall takes in new substances, such as silica and various salts, or as there is an elaboration and deposit of gum, pectose and lignin. Each living cell contains a viscid fluid, of extremely complex chemical composition – the protoplasm – a layer of which is in contact with the cell wall and connected by bridles with a central mass in which the nucleus containing the nucleolus is embedded. The protoplasm does not fill the whole cavity of the cell, but there is a large space filled with the watery sap.
The sap carries in solution certain sugars, together with glycogen and two varieties of glucose, and such organic acids and coloring matters as may already have been elaborated. Where metabolism is active, certain crystallizable nitrogenous bodies, as asparagin, leucin and tyrosin, with salts of potassium and sodium, are found, while in the vacuole there may be starch grains and some crystals of calcium oxalate. The protoplasm is chemically made up of proteids, of which two groups may be distinguished in plants. The first embracing the plastin, such as forms the frame work of the cell, and the second the peptones of the seeds, and the globulins found in the buds and in young shoots. These proteids all consist of carbon, hydrogen, nitrogen, oxygen, and sulphur, while plastin also contains phosphorus. In active growing cells the proteids are present in a quantity, which gradually diminishes as the cell becomes older, leaving the plastin as the organized proteid wall of the cell, while the globulins and peptones remain unorganized. The whole constructive metabolism of the plant is toward the manufacture of this protoplasm, the chemical decomposition and conversion of which liberates the energy which continues cell life.
In certain cells of the plant associated with the protoplasm, and presumably of a similar chemical composition, are little corpuscles, which contain the chlorophyl constituting the green coloring matter of plants, a substance which from its chemical construction and physiological function may have some important influence on the alkaloid formation in the Coca leaf. In these bodies the chlorophyl is held in an oily medium, which exudes in viscid drops when the granules are treated with dilute acids or steam. Although no iron has been found in these bodies by analysis, it is known that chlorophyl cannot be developed without the presence of iron in the soil. Gautier, from an alcoholic extract, calculated the formula C19H22N2O3, and called attention to the similarity between this and that of bilirubin, C16H18N203 – the primary pigment forming the golden red color of the human bile, which possibly may be allied to the red corpuscles of the blood. Chlorophyl, while commonly only formed under appropriate conditions of light and heat, may in some cases be produced in complete darkness, in a suitable temperature. Thus if a seed be made to germinate in the dark, the seedling will be not green, but pale yellow, and the plant is anӕmic, or is termed etiolated, though corpuscles are present, which, under appropriate conditions, will give rise to chlorophyll.
It has been found that etiolated plants become green more readily in diffused light than in bright sunshine. The process of chlorophyll formation neither commences directly when an etiolated plant is exposed to light, nor ceases entirely when a green plant is placed in darkness, but the action continues through what has been termed photo-chemical induction. From experiments to determine the relative efficacy of different rays of the spectrum it has been found that in light of low intensity seedlings turn green more rapidly under yellow rays, next under green, then under red, and less rapidly under blue. In intense light the green formation is quicker under blue than under yellow, while under the latter condition decomposition is more rapid.
The function of chlorophyl is to break up carbonic acid, releasing oxygen, and converting the carbon into storage food for the tissues, the first visible stage of which constructive metabolism is the formation of starch. The activity of this property may be regarded as extremely powerful when it is considered that in order to reduce carbonic acid artificially it requires the extraordinary temperature of 1300° C. (2372° F.). In the leaf this action takes place under the influence of appropriate light and heat from the sun in the ordinary temperature of 10°-30° C. (50°-86° F.). Plants which do not contain chlorophyl – as fungi – obtain their supply of carbon through more complex compounds in union with hydrogen.
Perhaps we are too apt to regard plants as chiefly cellulose – carbohydrates, and water, without considering the importance of their nitrogenous elements, for though these latter substances may be present in relatively small proportion, they are as essential in the formation of plant tissue as in animal structures. The carbohydrates of plants include starch, sugars, gums, and inulin. The starch or an allied substance, as has been shown, being elaborated by the chlorophyl granules, or in those parts of the plant where these bodies do not exist, by special corpuscles in the protoplasm, termed amyloplasts, which closely resemble the chlorophyl bodies. In the first instance the change is more simple and under the influence of light, in the latter light is not directly essential and the process is more complex, the starch formation beginning with intermediate substances – as asparagin, or glucose, by conversion of the sugars in the cell sap.
Just as in the human organism, assimilation in plant tissue cannot take place except through solution, so the stored up starch is of no immediate service until it is rendered soluble. In other words, it must be prepared in a way analogous to the digestion of food in animal tissues. This is done by the action of certain ferments manufactured by the protoplasm. These do not directly enter into the upbuilding of tissue themselves, but induce the change in the substance upon which they act. Chiefly by a process of hydration, in which several molecules of water are added, the insoluble bodies are rendered soluble, and are so carried in solution to various portions of the plant. Here they are rearranged as insoluble starch, to serve as the common storage tissue for sustenance. Thus it will be seen how very similar are the processes of assimilation in plants and animals, a marked characteristic between both being that the same elementary chemical substances are necessary in the upbuilding of their tissues, and particularly that activity is absent where assimilable nitrogen is not present.
Several organic acids occur in plant cells, either free or combined, which are probably products of destructive metabolism, either from the oxidation of carbohydrates or from the decomposition of proteids. Liebig regarded the highly oxidized acids – especially oxalic, as being the first products of constructive metabolism, which, by gradual reduction, formed carbohydrates and fats, in support of which he referred to the fact that as fruits ripen they become less sour, which he interpreted to mean that the acid is converted into sugar. The probability, however, is that oxalic acid is the product of destructive metabolism, and is the final stage of excretion from which alkaloids are produced, while it is significant, when considering the Coca products, that acids may by decomposition be formed from proteid or may by oxidation be converted into other acids.
Oxalic acid is very commonly found in the leaf cells combined with potassium or calcium. It is present in the cells of the Coca leaf as little crystalline cubes or prisms. Malic acid, citric acid, and tartaric acid are familiar as the products of various fruits. Tannic acid is chiefly found as the astringent property of various barks. Often a variety of this acid is characteristic of the plant and associated with its alkaloid. This is the case with the tannic acid described by Niemann in his separation of cocaine, which is intimately related to the alkaloids of the Coca leaf, just as quinine is combined with quinic acid and morphine with meconic acid. It has been suggested that the yield of alkaloid from the Coca leaf is greater in the presence of a large proportion of tannic acid.
Tannin is formed in the destructive metabolism of the protoplasm, as a glucoside product intermediate between the carbohydrate and the purely aromatic bodies, such as benzoic and cinnamic acids, which are formed from the oxidative decomposition of the glucosides. In addition to these are found fatty oils, associated with the substances of the cell, and essential oils, to which the fragrance of the flower or plant is due, and which are secreted in special walled cells. The resins are found as crude resins, balsams – a mixture of resin and ethereal oil with an aromatic acid, and gum resins – a mixture of gum, resin and ethereal oil. The ethereal oils include a great number of substances with varying chemical composition, having no apparent constructive use to the tissues, but, like the alkaloids, regarded merely as waste. Some of these products serve by their unpleasant properties to repel animals and insects, while others serve to attract insects and thus contribute to the fertilization of the flower, so all these bodies may be of some relative use.
The proteids of the plant are supposed to be produced from some non-nitrogenous substance – possibly formic aldehyde – by a combination formed from the absorbed nitrates, sulphates and phosphates, in union with one of the organic acids, particularly oxalic. The change being from the less complex compound to a highly nitrogenous organic substance, termed an amide, which, with the non-nitrogenous substance and sulphur, unite to form the proteid. The amides are crystallizable nitrogenous substances, built up synthetically, or formed by the breaking down of certain compounds. They are similar to some of the final decomposition products found in the animal body. Belonging to this group of bodies is xanthin, which Kossel supposed to be directly derived from nuclein, from the nucleus of the plant cell. But in whatever manner the amides are formed, it is believed they are ultimately used in the construction of proteid, and although this substance is produced in all parts of the plant, it is found more abundant in the cells containing chlorophyl. Proteids are found to gradually increase from the roots toward the leaves, where they are most abundant. This would seem to indicate that the leaf is the especial organ in which proteid formation takes place, and it is in this portion of the Coca plant that the excreted alkaloids are found most abundantly.
According to Schützenberger, the proteid structures are composed of ureids, derivatives of carbamide, and Grimaux considers they are broken by hydrolysis into carbonic acid, ammoniac and amidic acids, thus placing them in near relation with uric acid, which also gives by hydrolysis, carbonic acid, ammoniac acid and glycocol. In animal tissues the last product of excrementition is carbamide – or uric acid, while the compounds from which proteids are formed in plants have been shown to be amides. It has been shown in the laboratory that the chemical products from the breaking down of proteids are also amides, with which carbonic acid and oxalic acid are nearly always formed. The presence of hippuric acid in the urine of herbivorous animals, the indol and the skatol found in the products of pancreatic digestion (Salkowski), together with the tyrosin nearly always present in the animal body, has led to the supposition that aromatic groups may also be constituents of the proteid molecule.
All of this is of the greatest interest in the study of alkaloid production in connection with the fact, which has been proved, that when a plant does not receive nitrogen from outside it will not part with the amount of that element previously contained – in other words, the nitrogenous excreta will not be thrown off. Boussingault thought the higher plants flourished best when supplied with nitrogen in the form of nitrates, though Lehmann has found that many plants flourish better when supplied with ammonia salts than when supplied with nitrates, and this has been well marked in the case of the tobacco plant.
Nitric acid may be absorbed by a plant in the form of any of its salts which can diffuse into the tissues, the most common bases being soda, potash, lime, magnesia and ammonia. The formation of this acid, attendant upon the electric conditions of the atmosphere, may be one source of increase of vigor to the native soil of the Coca plant, where the entire region of the Montaña is so subject to frequent electrical storms. Then Coca flourishes best in soils rich in humus, and various observers have remarked that nitrogen is best fixed in such a soil. An interesting point in connection with which is that the ammonia supplied to the soil by decomposition of nitrogenous substances is converted into nitrous, and this into nitric acid, by a process termed nitrification, occasioned by the presence of certain bacteria in the soil to which this property is attributed. Proof of this was determined by chloroforming a section of nitrifying earth and finding that the process on that area ceased. The absorption of nitrogen by the Coca plant and the development of proteids is closely associated with the nitrogenous excreta from the plant, and the consequent production of alkaloids which we are attempting to trace.
The nitrogen of the soil, however induced, is transferred by oxidation into what has been termed the reduced nitrogen of amides which, in combination with carbohydrates, under appropriate conditions forms proteids, in which oxalic acid is an indirect product. Several observers consider the leaves as active in this process, because the nitrogenous compounds are found to accumulate in the leaf until their full development, when they decrease. This is illustrated by the fact that in autumn, when new proteids are not necessary to matured leaves, it accumulates in the protoplasm, from which it is transferred to the stem, to be stored up as a food for the following season’s growth.
It has been found that the nitrates, passing from the roots as calcium nitrate, are changed in the leaves by the chlorophyl in the presence of light with the production of calcium oxalate, while nitric acid is set free, and conversely, in darkness the nitrates are permitted to accumulate. This change is influenced by the presence of oxalic acid, which, even in small quantities, is capable of decomposing the most dilute solutions of calcium nitrate. The free nitric acid in combination with a carbohydrate forms the protein molecule, while setting free carbonic acid and water.
Cellulose, which we have seen is formed from protoplasm, is dependent upon the appropriate conversion of the nitrogenous proteid. When this formation is active, large amounts of carbohydrates are required to form anew the protein molecule of the protoplasm, and the nitrogenous element is utilized. When there is an insufficiency of carbohydrate material the relative amount of nitrogen increases because the conditions are not favorable for its utilization in the production of proteids, and this excess of nitrogen is converted into amides, which are stored up. When the carbohydrate supply to the plant is scanty in amount this reserve store of amides is consumed, just the same as the reserve fat would be consumed in the animal structure under similar conditions.
The relation between the normal use of nitrogen in plants is analogous to its influence in animal structure, while the final products in both cases are similar, the distinction being chiefly one in the method of chemical conversion and excretion due to the difference in organic function. Thus, although urea and uric acid are not formed in plants, the final products of both animals and plants are closely allied. We see this especially in the alkaloids caffeine and theobromine, which are almost identical with uric acid, so much so that Haig considers that a dose of caffeine is equivalent to introducing into the system an equal amount of uric acid.
There are numerous examples, not only in medicinal substances, but in the more familiar vegetables and fruits, which illustrate the possibilities of change due to cultivation. The Siberian rhododendron varies its properties from stimulant to a narcotic or cathartic, in accordance with its location of growth. Aconite, assafoetida, cinchona, digitalis, opium and rhubarb are all examples which show the influence of soil and cultivation. Indeed similar effects are to be seen everywhere about us, certain characteristics being prominently brought forth by stimulating different parts of the organism, so that ultimately distinct varieties are constituted. The poisonous Persian almond has thus become the luscious peach. The starchy qualities of the potato are concentrated in its increased tuber, and certain poisonous mushrooms have become edible. The quality of the flour from wheat is influenced by locality and cultivation. The tomato, cabbage, celery, asparagus, are all familiar examples which emphasize the possibility of shaping nature’s wild luxuriance to man’s cultured necessity.
The chemical elements which are taken up by a plant vary considerably with the conditions of environment, and the influence of light in freeing acid in the leaf has been indicated. These conditions necessarily modify the constituents of the plant. When metabolism is effected certain changes take place in the tissues, with the formation of substances which may be undesirable to the plant, yet may be medicinally serviceable. Such a change occurs in the sprouts of potatoes stored in the dark, when the poisonous base solania is formed, which under normal conditions of growth is not present in the plant. A familiar example of change due to environment is exhibited in the grape, which may contain a varying proportion of acid, sugar and salts in accordance with the soil, climate and conditions of its cultivation, nor are these variations merely slight, for they are sufficient to generate in the wine made from the fruit entirely different tastes and properties.
The Basic Nature Of Alkaloids
In view of these facts, it seems creditable to suppose that by suitable processes of cultivation the output of alkaloids may be influenced in plants, and such experiments have already been extensively carried out in connection with the production of quinine. When attention was directed to the scientific cultivation of cinchona in the East, it was remarked that when manured with highly nitrogenous compounds the yield of alkaloid was greatly increased. This is paralleled by the fact that when an animal consumes a large quantity of nitrogenous food the output of urea and uric acid is greater.
Alkaloids are regarded as waste products because they cannot enter into the constructive metabolism of the plant, though they are not directly excreted, but are stored away where they will not enter the circulation, and may be soon shed, as in the leaf or bark. Though, as indicating their possible utility, it has been shown experimentally that plants are capable of taking up nitrogenous compounds, such as urea, uric acid, leucin, tyrosin, or glycocol, when supplied to their roots. In some recent experiments carried out at the botanical laboratory of Columbia University, I found that plant metabolism was materially hastened under the stimulus of cocaine.
The influence of light in the formation of alkaloids has already been shown. Tropical plants which produce these substances in abundance in their native state often yield but small quantities when grown in hot houses, indicating that a too intense light is unfavorable, probably in stimulating a too rapid action of the chlorophyl, together with a decomposition of the organic acid. Some years ago the botanist. Dr. Louis Errera, of Brussels, found that the young leaves of certain plants yielded more abundant alkaloid than those that were mature. Following this suggestion, Dr. Greshoif is said to have found that young Coca leaves yield nearly double the amount of alkaloid over that contained in old leaves gathered at the same time. In tea plantations the youngest leaves are gathered, but it has always been customary to collect the mature leaves of the Coca plant, and these have usually been found to yield the greatest amount of alkaloid. The probability is that the amount of alkaloid present in the Coca leaf is not so much influenced by maturity as it is by the period of its gathering.
As regards the temperature at which growth progresses most favorably, Martins has compared each plant to a thermometer, the zero point of which is the minimum temperature at which its life is possible. Thus, the Coca shrub in its native state will support a range from 18° C. (64.4° F.) to 30° C. (86° F.), an influence of temperature which is governed by the proportion of water contained in the plant. It has been found, from experiments of cultivation, that Coca will flourish in a temperature considerably higher than that which was originally supposed bearable, though the alkaloidal yield is less than that grown more temperately. The life process of any plant, however, may be exalted as the temperature rises above its zero point, though only continuing to rise until a certain height is reached, at which it ceases entirely. In the cold, plants may undergo a similar hibernation as do certain animals when metabolism is lessened, though long-continued cold is fatal, and frost is always so absolutely to Coca. The influence of temperature on metabolism tends to alter the relations between the volume of carbonic acid given off and the amount of oxygen absorbed. Under a mean temperature these relations are equal, while in a lower temperature more oxygen is absorbed in proportion to the carbonic acid given off, and oxygen exhalation ceases entirely below a certain degree.
A relatively large proportion of water in a plant determines its susceptibility to climatic conditions. Thus freezing not only breaks the delicate parenchymatous tissues, but alters the chemical constitution of the cells, while too high a temperature may prove destructive through a coagulation of the albumen. The appearance of plants killed by high or low temperature being similar. Roots are stimulated to curve to their source of moisture, and their power for absorption is more active in a high than in a low temperature, but as absorption is influenced by the transpiration of the plant, it is less active in a moist atmosphere, unless the metabolic processes of the plant occasions a higher temperature than the surrounding air. Such activity would be increased by the heat of the soil about the roots, and is probably manifest in the Coca plant through the peculiar soil of the Montaña.
The elevation at which a plant grows has an influence upon the absorption by the leaf. Thus it has been observed that while a slight increase in the carbonic acid gas contained in the air is favorable to growth, a considerable increase is prejudicial, while an increase or diminution of atmospheric pressure materially influences plant life. In some tropical countries Coca will grow at the level of the sea, provided there is an equable temperature and requisite humidity. Although in Peru Coca flourishes side by side with the best coffee, it will not thrive at the elevations where the coffee plant is commonly grown in either the East or West Indies. In Java, where experiments have been made in cultivating Coca, it has been stated that there is no perceptible difference in the alkaloidal yield due to the influence of elevation, while in the best cocals of Peru it is considered that the higher the altitude at which Coca can be grown the greater will be the alkaloidal yield. This is possibly effected by similar influences to that governing the aromatic properties developed in the coffee bean, which have been found more abundant when coffee is grown at an elevation, yet without danger of frost. This may be attributed to slower growth and a consequent deposit of nitrogenous principles instead of their being all consumed through a rapid metabolism.
It is therefore evident that as these several physical conditions have a marked bearing upon the life history of all plants, the more limited the range for any of these processes in any particular plant, the more it will be influenced. Thus in an altitude too high, the leaf of the Coca plant is smaller and only one harvest is possible within the year, while in the lower regions where the temperature exceeds 20° C. (68° F.) vegetation may be exuberant, but the quality of leaf is impaired. The electrical conditions of the atmosphere, it has been shown, have an important bearing upon the development of Coca, through the influence of the gases set free in the atmosphere and the possible slight increase of nitric acid carried to the soil.
It was thought by Martins that the mosses and lichens which are found upon the Coca shrubs were detrimental to the plant through favoring too great humidity. In the light of our knowledge on the development of alkaloids, however, it has seemed to me that here is an opportunity for very extended experimentation, as may be inferred from a reference to the alkaloidal production of cinchona. At first efforts were made to free the cinchona trees from the lichens and mosses which naturally formed upon them; but it was discovered accidentally that those portions of the trees which nature had covered in this manner yielded an increased amount of alkaloid. When cinchona plantations were started in Java, experiments made upon the result of this discovery prompted a systematic covering of the trunks of the trees artificially with moss, which was bound about them to the height from which the bark would be stripped. At first very great pains was taken to collect just an appropriate kind of moss, which it was supposed from its association with the tree in its native home would be essential, but later experiments proved that any form of covering which protected the bark from light increased this alkaloidal yield. So that to-day this process, which is known as “mossing,” is one of the most important in the cultivation and development of cinchona.
A Source Of Profound Confusion
The chief interest of Coca to the commercial world has centered upon its possibilities in the production of the one alkaloid, cocaine, instead of a more general economic use of the leaf. Because of this, much confusion of terms has resulted, for chemists have designated the amount of alkaloids obtained from the leaf as cocaine, although they have qualified their statement by saying that a portion of this is un- crystallizable. Numerous experiments have been conducted to determine the relative yield of cocaine from the different varieties of Coca, and when uncrystallizable alkaloids have been found the leaf has been condemned for chemical uses. It will thus be appreciated how a great amount of error has been generated and continued. The Bolivian or Huanuco variety has been found to yield the largest percentage of crystallizable alkaloid, while the Peruvian or Truxillo variety, though yielding nearly as much total alkaloid, affords a less percentage that is crystallizable, the Bolivian Coca being set apart for the use of the chemists to the exclusion of the Peruvian variety, which is richest in aromatic principles and best suited for medicinal purposes. As a matter of fact, the Peruvian Coca is the plant sought for by the native users.
There is not only a difference in the yield of alkaloid from different varieties of Coca, but also a difference in the yield from plants of one variety from the same cocal, and it would seem possible by selection and propagation of the better plants to obtain a high percentage of alkaloid. At present there is no effort in the native home of Coca toward the production of alkaloid in the leaf through any artificial means. Regarding the quality of alkaloid that has been found in the different plants, the Peruvian variety has been found to contain equal proportions of crystallizable and uncrystallizable alkaloid, while the Bolivian variety contains alkaloids the greater amount of which are crystallizable cocaine. Plants which are grown in conservatory, even with the greatest care, yield but a small percentage of alkaloid, of which, however, the uncrystallizable alkaloid seems more constant while the relative amount of cocaine is diminished. In leaves grown at Kew .44 percent, of alkaloid was obtained, of which .1 percent, was crystallizable. From experiments of Mr. G. Peppe, of Renchi, Bengal, upon leaves obtained from plants imported from Paris, it was found that leaves dried in the sun yielded .53 per cent, of alkaloid, of which .23 per cent was uncrystallizable. The same leaves dried in the shade on cloth for twenty hours, then rolled by hand, after the manner in which Chinese tea is treated, then cured for two and a half hours and dried over a charcoal fire and packed in close tins, yielded .58 per cent, of alkaloid, of which .17 per cent, was uncrystallizable.
It is probable that each variety of Coca has a particular range of altitude at which it may be best cultivated. The Bolivian variety is grown at a higher altitude than Peruvian Coca, while the Novo Granatense variety has even been found to thrive at the level of the sea. Among Coca, as among the cinchona certain varieties yield a large proportion of total alkaloids, of which only a small amount is crystallizable. The Cinchona succirubra yields a large amount of mixed alkaloids, but a small amount of quinine, while Cinchona Calisaya yields a smaller amount of mixed alkaloids and a large amount of crystallizable quinine. A few authors who have referred to the alkaloidal yield of Coca leaves have casually remarked that the plants grown in the shade produce an increased amount above those grown in the sun, which would appear to be paralleled by the formation of chlorophyl and the production of proteids, both of which have so important a bearing upon the metabolism of the plant and the final nitrogenous excretion.
This subject is one full of interest, yet so intricate that it has not been possible for me to elaborate the suggestions here set forth in time to embody my investigation in the present writing, though I hope to present the result of my research at no very distant date. It would seem that sufficient has been shown, however, to indicate the possibility of modifying plant metabolism under appropriate conditions of culture so as to influence the development of the alkaloidal excreta. The comparisons between plant and animal life may have proved of sufficient interest to enlist attention to the higher physiology in which will be traced the action of Coca.
Another well-done study is showing that medical researchers have now firmly established the relationship between Brain Inflammation and Depression. Brain inflammation rarely occurs by itself; much more commonly, the brain is inflamed because the whole body is inflamed. Put another way, if you are inflamed, your brain is probably inflamed too. While whole body inflammation has a number of possible origins, none are more common than (1) autoimmune disease and (2) inflammatory diets. (Which are quite likely themselves closely linked)
A wide range of diseases from heart disease to obesity, and from ME/CFS to Depression are now clearly associated with, if not caused by whole body inflammation. Hundreds of billions of dollars are spent “treating” these diseases, but the suffering and dying have not slowed down. If anything, human life on planet Earth is approaching, or at least edging up on some kind of terminal disease that we don’t even have a name for yet. But you can bet that it will work its deadly toll through some kind of inflammation.
Given the enormous range of sources of inflammation in today’s societies worldwide, and given that there are no good, simple ways for people in the grip of whole body inflammation to get it under control, you would think that some group of responsible scientists somewhere, would run even a small, well-controlled study on whether or not Coca leaf Tea could treat even some of the common inflammatory conditions.
Medical researchers are portrayed in the media as risk-takers, and some may be. There may even be some innovative thinkers working today. But so far none appear to be able to learn, or even take a hint from history.
You would think, wouldn’t you, that if a responsible medical researcher who was interested in inflammatory processes read the following few paragraphs they might suggest a worthwhile direction for some inexpensive, potentially breakthrough research.
Well, that’s what I’m hoping. These three quotes are from 600+ pages of hyperlinked historical documents in “The Coca Leaf Papers” that I published in 2012. These observations were made by doctors living and practicing well over 100 years ago, and sum up their lifetimes of observations of the healing effects of pure, natural Coca Leaf.
I’m still waiting for those first clinical trials of Coca Leaf, aren’t you? There are lots of Pig Pharma studies on “treatments” costing six-figures per treatment, but not one peep on that little cup of tea.
Dr. William Tibbles
” Although our materia medica includes many valuable remedies for human affliction, it is a matter of certainty that in all cases where the animal vitality is failing, or where exhaustion or disease exist, Erythroxylon Coca is decidedly superior to every other remedy at present known. It will work effects such as no other single drug will produce, and it possesses the great advantage of not causing, when its use is relinquished or discontinued, the slightest reaction or depression.
So valuable are the properties, and so extensive the field in which this new remedy may be employed in the amelioration of human suffering, that the author now brings it before the public, in the hope that a great amount of present affliction may be removed, and, in the future, prevented.“
Dr. William Searles
“… increased arterial tension throws a greater strain upon the heart, which becomes overtaxed, dilated, and there are produced breathlessness, a sensation of lightness in the head, etc. Coca, by its toning action on the nervous system, increases the amount of nervous influence over the whole organism, diminishes the waste of tissue, regulates the various functional actions – as circulation, excretion, etc., and prevents such results as above given.
Thus its efficacy as a therapeutic agent in all forms of disease cannot be doubted. In consumption, in inflammation, in fevers, in which states of the system there is an increase in temperature, disorder of nutrition, abnormal disintegration of the tissues of the body’s nervous and muscular fibres, increased production and excretion of urates, carbonic acid, etc.; in the brain exhaustion consequent upon mental labour, and in the fatigue produced by physical exercise.
In all states and conditions of men coca is invaluable both as a preventive of exhaustion and a repairer of wasted tissue. In all the years through which I have used these leaves, I have administered them in large and small doses, to man and animals, without inducing, in any one case, injurious effects, but always, on the contrary, the beneficial results required.”
Wm. TIBBLES,MD, Syston, Leicester. N 2
“The discovery of the Western Continent, whether due to the forethought or ignorance of Columbus, or to the hardihood of the Norsemen several centuries before his time, brought a multitude of bounties to humanity. Among these none is greater than the countless plants which have been gradually unfolded to usefulness by the processes of science. Particularly is this true of the economic and medicinal plants of South America, which on the eastern declivity of the Andes and towards the valley of the Amazon, spring forth in all the luxuriance of the tropical jungle, over a vast portion of which it is supposed the foot of man has never trodden.
In this locality – and among this wild profusion, grows a beautiful shrub, the leaves of which in shape somewhat resemble those of the orange tree, but in color are of a very much paler green, having that exquisite translucence of the most delicate fern. The properties of this plant more nearly approach that ideal source of endurance than is known to exist in any other one sub stance.
Its leaves have been used by the natives of the surrounding country from the earliest recollection, as a masticatory, as a medicine, and as a force sustaining food. Its use is not confined to emergency, nor to luxury, but as an essential factor to the daily life work of these people.
As a potent necessity it has been tenderly cared for and carefully cultivated through the struggles, trials and vituperation it has been the occasion of during so many hundreds of years, until to-day its cultivation forms the chief industry of a large portion of the natives and a prominent source of revenue to the governments controlling the localities where it is grown.
It will be shown by ample testimony that Coca is not only a substance innocent as is tea or coffee – which are commonly accepted popular necessities – but that Coca is vastly superior to these substances, and more worthy of general use because of its depurative action on the blood, as well as through its property of provoking a chemico-physiological change in the tissues whereby the nerves and muscles are rendered more capable for their work.
Strong as may appear this assertion, I believe that the facts here presented will amply indicate that sufficient has not been said upon the benefits to accrue from the liberal use of Coca, Indeed, our knowledge of it is yet in its infancy, and if this present writing will but excite others to continue these investigations and experiments. Coca will achieve the position it should maintain as an aid and support to humanity worthy the greatest popularity and the highest possible respect.
Dr. Golden Mortimer
People of conscience rightfully condemn the Nazi looting of art and cultural artifacts from Jewish victims of the Holocaust, and from homes and museums around Europe. People also rightfully condemn the berserk destruction of cultural and historical treasures in Iraq and Afghanistan by ISIS and the Taliban.
There is a growing body of international law that condemns and demands reparations on the part of former colonial powers like Britain, France, Belgium and The Netherlands whose military and “explorers” looted cultural and historical treasures of Greece, Egypt, Iraq, India, Indonesia, Africa and elsewhere in their Empires. The Spanish are certainly near the top of any list of looters of cultural and historical artifacts with their centuries-long conquest and domination of the Indian civilizations of Latin America.
And of course it can hardly be disputed that the Americans top the list of looters with their genocide against Native Americans and blatant theft of their ancient homelands, along with widespread looting of their cultural and historical artifacts, desecration of their graves, and theft of their cultural heritage. When this history is combined with the destruction and enslavement of entire African civilizations, and the forced obliteration of not only whole families and tribes but whole histories, Americans are definitely at the top of any list of historical and cultural criminals.
All of the victims of these various exercises of colonial avarice, hatred and slaughter are at some stage in seeking reparations. The Greeks want their temples back from the British. The Egyptians want the bones and treasures of their ancient Kings returned. Native Americans are demanding the return of their sacred objects and the bones of their ancestors from the Smithsonian. The Iraqis who have seen their Mesopotamian heritage scattered to the winds for centuries are currently being victimized by a blow-dried reincarnation of Jim & Tammy Faye in the person of the “Christian” owners of the tacky little “Hobby Lobby” chain in the US that is charged with large-scale looting on ancient artifacts in the Middle East. These elaborately coiffed smiley-face Oklahomans of course deny everything, pleading that they had no idea that these little ole’ tiles were invaluable cultural artifacts.
Cultures worldwide are demanding the same of museums in France, Belgium and The Netherlands. The Chinese are demanding the return of cultural and historical treasures looted by the American-backed Chiang Kai Shek. American Black people are demanding reparations for the theft and brutalization of their families, cultures and history. Latin American cultures are demanding that Spain , Portugal and the Catholic Church return the wealth in gold, silver, culture and history stolen from them over the centuries of Colonial domination.
However, in the midst of all this worldwide outcry against theft of cultural and historical heritage by force and stealth, at least one enormous crime against Native People has been completely overlooked, and I am proposing that the people of Bolivia and Peru, who are the victims of this particular crime, organize and pursue legal remedy under the same body of international law that has begun to recognize the rights of other Native People worldwide.
The crime I am referring to is the theft of the Coca Plant by the European pharmaceutical industry that, since the 1840’s, has made hundreds of billions of dollars from the theft of this Sacred Plant of the Incas and has not paid one penny in reparation or shared any of the huge profits that this industry has enjoyed for over 150 years. Specifically, I am suggesting that Bolivia and Peru jointly sue the German Pharmaceutical company Merck, which was responsible for first looting Coca Plants from Bolivia and Peru and then extracting the alkaloid Cocaine from those plants, and then making Cocaine the core of the company’s fortunes as it grew into the globally dominant pharmaceutical giant of today.
The Coca Plant is indigenous to only one place in the world – the southern Andes – so Merck cannot claim that they took a plant that was readily available worldwide and simply exercised their scientific genius in producing Cocaine. The plants that Merck used to create mountains of gold from a few green leaves came from only one place, and were the cultural and historical heritage of only one People – the Native peoples who today live in poverty in Andes, remote from even a handful of the wealth so jealously guarded by the German pharmaceutical industry and others worldwide who profit from the cultural heritage of the Incas – companies like Coca Cola, who should also be named in any lawsuit for reparations brought by representatives of the Native People of Bolivia and Peru.
The art looted by the Nazis is being returned to the rightful owners under the law, and the families and descendants of those owners are rightfully being compensated. The stolen art, artifacts and bones of ancient civilizations in Greece, Egypt and elsewhere are gradually being pried loose from the talons of the museums erected by Colonial powers to display their loot. Even the American Smithsonian is finally, reluctantly recognizing that it has no right to make the corpses of Native Americans part of their “display”, and are, while doing a lot of foot-dragging, gradually returning the bones and cultural and historical loot stolen from the Native American people. And although there is enormous opposition among the elite and their toadies toward paying reparations to American Black people, at least there is some movement among American Black people themselves to reclaim parts of their stolen cultural and historical heritage.
So why shouldn’t Merck, Coca Cola and others that have profited from the theft of the heritage of the Incas be taken before the bar of international justice and stripped of at least a major portion of the profits that they have made from the theft of the cultural/historical heritage of the descendants of the Incas? The court of jurisdiction would also be responsible for assuring that the money recovered in the name of the descendants of the Incas was not re-looted by politicians in those countries, and instead went into a closely supervised non-profit international organization that was severely limited in the salaries it could pay and the administrative overhead it could charge.
I think that this is the right thing to do, and I think it should be done beginning now. Are you listening, President Morales? You have an historic opportunity to force the greedy capitalists of Merck, Coca Cola and other evil corporations to crawl on their knees dragging wagonloads of stolen wealth back to the people who are its rightful owners.
Just do it. Por favor.
One of the looming tragedies in America is what Daffy Don and his hate-filled followers are about to do to access to health care for poor people.
One part of the tragedy is that so many of the people who oppose Daffy Don’s attack on the poor wind up fighting for the right of poor people to have access to a failed medical system that can do nothing for them but hook them on the products of Pig Pharma without even beginning to treat or cure them of the killer diseases that afflict them.
But an even greater tragedy is that so many of the health conditions that plague poor people especially hard like Diabetes, Obesity, Heart Disease and Depression could be effective treated and cured by a few cups of Coca Leaf tea a day, resulting is far less need for health insurance, pharmaceuticals, or ER and doctor visits.
This isn’t a pipe dream, although it is a dream. I’ve been providing documentation for many years in this blog for the efficacy and safety of Coca Leaf in treating and potentially reversing and curing many of the diseases that maim and kill poor people in the US. I’ve even provided what I believe are cogent arguments for the use of Coca Leaf in treating diseases like Alzheimer’s that afflict and torture people without regard to their economic status.
The bottom line is that all of the hater’s arguments about the costs of ObamaCare could be undercut and rendered pointless if American’s simply had full legal access to Coca Leaf medicines, which they could brew up themselves on their kitchen stoves. I’ll bet that within a year or two of having cheap, daily access to Coca Leaf tea the need for “health care” would decrease so dramatically that even the most hate-filled of Daffy Don’s followers would have to admit that it’s a good idea.
In fact, I am quite sure that many of these obnoxious little Brown Shirts would be clandestinely sipping a few cups of Coca Leaf tea every day for their high blood pressure and sick hearts and who knows – they might even mellow out a bit.
Nah – that’s hoping for too much, and for the wrong people.
But those who are stunned by how this administration is turning the War On Poverty into the War On The Poor ought to get behind medical Coca Leaf with all the energy that they are now, quite rightfully, devoting to the cause of Medical Cannabis. That would take care of a huge part of the problems that poor people have with the so-called health care system in the US.
The Government of Peru is a major buyer of Coca Leaf in the Valley of the Apurimac-Ene-Mantaro Rivers, referred to in ever-charming government acronym style as “The VRAEM”. This Valley lies at the heart of the Andean mountain chain and could easily have been the model for Shangri-la. As it is, the Peruvian government, in league with the US Police State, has turned the Valley of the Apurimac-Ene-Mantaro Rivers into a war zone targeting peaceful Coca growers.
Interestingly the Peruvian government is also a major buyer of the Valley’s Coca Leaf, but the government buyers are well-known as cheapskates. That’s probably because – officially – government buyers and selected foreign buyers like Coca Cola are supposed to be the only buyers in the valley. They figure they’re doing the Coca growers a favor.
Of course, the Cocaine Cartels beg to differ with that, as do a substantial proportion of valley residents. And so there is no peace in the valley.
The Peruvian government owns and controls the non-Cocaine use of Coca Leaf through a monopoly named ENACO. This state-run company produces the official line of Coca tonics, medicines drinks and snacks for domestic consumption.
Peru’s politicians are in the Coca Leaf Remedios business because Coca Remedios are so deeply ingrained in Peruvian society that their use cannot be stopped – oh, and also because it’s a handy way to make some very nice revenue.
However, private entrepreneurs are not allowed to compete with the government monopoly, so Peruvian Coca Leaf products remain stuck with an incongruous “Soviet” look and excruciatingly ho-hum marketing. Too bad for Peru – Bolivian entrepreneurs and government officials are already making creative headway in the world markets for Coca Leaf and Coca Leaf medicines. (Pretty soon some country in Europe like the Netherlands or France is going to open up to Coca leaf entrepreneurs. The US is probably going to keep its Federal asshole puckered but one or two of the states ought to give Coca Leaf legalization a good hard look. )
Meanwhile, back in Coca Valley. At the same time that it low-balls the farmers’ Coca Leaf and makes cheesy Coca Leaf products, the Peruvian government wages war against any “extra” Coca growing by the people of Coca Valley. If they grow more than they are told to by the government, or if they refuse to sell to ENACO because of its ridiculous prices for their precious leaf, GOP burns and poisons their fields and makes their lives as miserable as possible. After all, their bottom-line motive is to satisfy the requirements of the US Police State that wants to be able to show the world that Peru is trying very, very hard to eradicate illicit Cocaine production. Very hard.
But Aha! Peru has come up with a plan! GOP wants the people of Coca Valley to grow only enough Coca to satisfy the government’s requirements, and then to convert to growing crops like bananas and cocoa – assisted of course by friendly “experts” from the US and UN.
Of course if you are a farmer in Coca Valley and your family has been growing Coca for generations and you don’t happen to like the chintzy prices the government is willing to pay, are you going to let the police rip out your Coca plants and make you start over with Bananas? Quite a few Coca Valley residents have not been pleased when approached by men with guns proposing this plan, and a few have gotten downright rowdy. Thrown rocks ‘n stuff. You know – terrorism.
So to complete the farce the Peruvian government declared the VRAEM a war zone a few years back, it ever since has been battling against the quickly shrinking remains of the once-powerful Shining Path rebels – as of late 2015 SL is down to under 100 guerillas, mostly old men and teenagers.
To go after this fearsome band the Peruvian government keeps sending in waves of troops, missiles and helicopters, while the US leaps in with space-based surveillance, military aircraft, dark ops and night raiders, chemical warfare assistance and high tech drones. All this firepower is arrayed against ragtag remnants of what was once a well-organized and very effective rebellion.
These survivors fight on, using the vast forests and jungles of the Coca Valley, an area the size of Switzerland, to hide in.
So this is the threat – a hundred tired rebels who are definitely at the end of their Shining Path. Can you imagine, a hundred guys getting together in the mountains almost anywhere else in the world and the central government spending $250 Million a year to try to get rid of the rebels and eradicate a few thousand hectares of croplands at the same time – and failing?
“The Peruvian government’s (2014) counternarcotics strategy includes ambitious goals for eradication, interdiction, and alternative development, and addresses associated issues such as the control of precursor chemicals, organized crime, money laundering, and the rule of law. The Humala Administration increased its counternarcotics budget from $220 million in 2012 to $256 million in 2013. For the first time, Peru contributed $11.6 million towards eradication efforts and concomitant aviation support, which historically has been funded by the United States.” US Department of State
OK, so the Peruvian government spends $256 Million of mostly US money a year to – what – combat terrorism and cocaine trafficking and deal with other related dangers to the children, like free speech? And the US is right there helping out with money, technology, guns and manpower, just like the US was when the Fujimori government, funded by US foreign aid money, forcibly sterilized hundreds of thousands of Indian women in the 1980s in so-called “population control” programs.
Speaking of terrorism, let’s look at the terrorist activities of the Shining Path guerillas that are being used to justify all this government-initiated violence a little more closely.
So, how big a threat to the peace and tranquility of Peru is the Shining Path, actually? Here’s the US Department of State list of every one of the terrorist incidents involving the Shining Path in 2014. (Don’t worry – it isn’t a real long list)
- On April 9, Peruvian police arrested 28 leaders of the Movement for Amnesty and Fundamental Rights – a front organization that advocates for the release of imprisoned SL founder Abimael Guzman. Those arrested included two of Guzman’s long-time lawyers, Afredo Crespo and Manuel Fajardo. The 28 were charged with terrorism and terrorist financing using narcotics revenue. On August 4, the National Anti-Terrorism Court, citing lack of evidence, ordered that the 28 be released from pre-trail detention. Although the court ordered the detainees released, it did keep the charges intact so the trial can move forward.
- A May 16 clash between security forces and the SL in the Junin region left one SL guerilla dead and another wounded. The rest of the column was able to escape, but soldiers recovered weapons, ammunition, and communication equipment.
- On June 17, a combined Peruvian military and police force killed three SL terrorists in the VRAEM emergency zone. The joint patrol recovered a number of weapons, including a heavy machine gun that SL fighters reportedly stripped from a Russian-made Mi-17 helicopter they shot down in a 2009 attack that killed three soldiers.
- In August, security forces rescued six adults and three children from a work camp in the VRAEM used by SL to provide food and logistic support for its members.
- In August, police officers in the UHV arrested Oscar Silva, who is believed to have been the second-in-command to “Comrade Artemio,” who was captured in February 2012.
- In September, soldiers rescued 11 people, including six children, who were being forced to work for SL in Junin’s Satipo district.
- On November 2, security forces announced the arrest of Filemon Huillcayaure, considered one of the top financiers of SL in the VRAEM.
OK – there you are. That’s the Peruvian government’s 2014 body count in the US-sponsored War On Narco/Terror in Coca Valley. The totals include: 0 soldiers dead or wounded; 4 SL terrorists killed, 1 wounded; and 20 people including children rescued from slave labor for the Shining Path.
And that’s after a full year of running around this valley the size of Switzerland with thousands of troops, helicopters, attack jets, tanks, HumVees, guns and rockets, and the latest ground, air & space-based surveillance technology courtesy of the US. All this technology and manpower chasing approximately 100 Shining Path guerillas (now minus 4) as they shake down Coca growers, take pot shots at soldiers, hide in the jungle, enslave the occasional villager, and make Coca Base to generate an income.
So, now that we all know how well the “War On The Gang Of 100 Terrorists” is going – how about the “War On Coca Plants”?
Well, according to a 2014 roundup (sic) by the US Dept. of State, Bureau Of International Narcotics And Law Enforcement Affairs
“Peru remained the world’s top potential producer of cocaine for the third consecutive year, and was the second-largest cultivator of coca, with an estimated 50,500 hectares (ha) of coca under cultivation in 2012, the most recent year for which data is available. The majority of cocaine produced in Peru is transported to South American countries for domestic consumption, or for onward shipment to Europe, East Asia, and Mexico via private and commercial aircraft, and land and maritime conveyances. Peru is a major importer of precursor chemicals used for cocaine production.
“ President Ollanta Humala dedicated substantial resources to implement Peru’s 2012-2016 counternarcotics strategy. The strategy calls for a 200 percent increase in the eradication of illicit coca by 2016. The Government of Peru remains on pace to meet its ambitious targets in this area, and in 2013 eradicated in the Monzón River Valley, a hostile area with little state presence, for the first time in decades. Sendero Luminoso (SL or Shining Path) operating in the Apurimac-Ene-Mantaro River Valley (VRAEM) relied on cocaine trafficking for funding, and killed and wounded several police and military personnel during counternarcotics operations.”
Oops. It looks like even with hundreds of millions of dollars, armadas of military-scale technology, thousands of heavily armed soldiers and police, and humungous firepower applied year after year, you still can’t (or conveniently don’t want to) deal with 100 guerillas operating in an area the size of Switzerland, and at the same time in spite of this all-out War you also still have the distinction of being the world’s top potential producer of cocaine for the third consecutive year, and you were the second-largest cultivator of coca in 2014.
This whole US-promoted War On Drugs/War On Terror thing really isn’t working for you is it?
Respectfully, I have a suggestion to offer.
Peru has a world-class renewable natural resource in the Coca plant and the people who have grown it for centuries. Why not go with what you have instead of playing a losing game in return for Yankee dollars? Why not just tell the US to go home, make peace with the Cartels and let them make and export all the Cocaine they want as long as they pay taxes, work with the indigenous people to build a Coca Leaf-based economy throughout the country, build a health industry based on Coca Leaf treatment at spas scattered throughout the mountains, and allow private enterprise to apply the entrepreneurial spirit to development and global sales of Coca-based medicines?
Next, pay off Shining Path and let them go home for God’s sake – including those you are holding in prison. I imagine that $50-$100K per SL guerilla would do it – a total of $5-10 Million (one-time investment) to get the whole hundred of them to lay down their weapons, for which they receive amnesty and a piece of land to grow Coca. And the SL in prison who agree to go home and live peacefully ought to get the same deal.
So Government of Peru, instead of spending hundreds of millions every year on a couple of wars that are going nowhere and aren’t even yours, plus terrorizing whole communities of your People, why not lead the world and declare that Coca is a gift from nature and that the Peruvian government will no longer stand in the way of those who wish to make their living by growing and making products from it – including Cocaine. What the rest of the world thinks shouldn’t matter.
I mean, hey there, government of Peru – don’t you have better things to do than chase 100 members of the Gang Who Can’t Shoot Straight, a bunch of peaceful Coca growers, and gangs of very determined Cocaine makers? Didn’t that US-sponsored clown Fujimori bring down enough evil on Peru to make the government finally decide to work for rather than against the People? If everybody’s happy in Coca Valley who cares what the US thinks?
It can happen. The US isn’t so tough anymore. Just ask your neighbors in Bolivia.